Recombinant Rabbit Anti-TSPO Antibody (clone R01-7E6) (CAT#: VS3-FY1493)
This product is a recombinant rabbit antibody that recognizes TSPO. This antibody has been reported for use in Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation. The clone R01-7E6 is specific for human, mouse TSPO. The antigen is synthetic peptide of human pbr.
Specific Inquiry
WB
Figure 1. Recombinant Rabbit Anti-TSPO Antibody (clone R01-7E6) in WB.
Western Blot analysis of PBR/TSPO in 3T3, Hela lysates using PBR Antibody.
IHC-P
Figure 2. Recombinant Rabbit Anti-TSPO Antibody (clone R01-7E6) in IHC-P.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using PBR antibody. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
Specifications
- Immunogen
- Synthetic peptide of human PBR.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse TSPO
- Species Reactivity
- Human, Mouse
- Clone
- R01-7E6
- Applications
- Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
- Conjugate
- Unconjugated
- MW
- Calculated MW: 11 kDa; Observed MW: 19 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry-Paraffin: 1/50-1/100
Immunofluorescence: 1/50-1/200
Immunoprecipitation: 1/20
Target
- Alternative Names
- Translocator Protein; Peripheral-Type Benzodiazepine Receptor; Mitochondrial Benzodiazepine Receptor; BZRP; PKBS; MBR; PBR; Peripheral-Type Benzodiazepine Receptor/Recognition Site; Benzodiazepine Peripheral Binding Site; Benzodiazapine Receptor (Peripheral)
- Gene ID
- 706
- UniProt ID
- B1AH88
- Sequence Similarities
- Belongs to the TspO/BZRP family.
- Cellular Localization
- Membrane, Mitochondrion
- Protein Refseq
- NP_000705.2; NP_001243459.1; NP_001243460.1
- Function
- Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity).
Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
Chicken IgY Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3352z | Mouse Anti-TSPO Recombinant Antibody (clone 32B5) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| MRO-1180-CN | Rabbit Anti-TSPO Recombinant Antibody (clone CBACN-436) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-2109-CN | Rabbit Anti-TSPO Polyclonal Antibody (MRO-2109-CN) | WB, IHC | Rabbit IgG |
| ZG-0610U | Rabbit Anti-TSPO Recombinant Antibody (clone 23G2) | ELISA, WB, IHC, IF, FC, IP | Rabbit IgG |
| VS3-CJ868 | Rabbit Anti-TSPO Recombinant Antibody (VS3-CJ868) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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