Recombinant Anti-TYRO3 Vesicular Antibody, EV Displayed (VS-0425-YC436)

CAT#: VS-0425-YC436

The Recombinant Anti-TYRO3 Vesicular Antibody, EV Displayed (VS-0425-YC436) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TYRO3-expressed cells or tissues. The TYRO3 is a receptor kinase involved in cellular survival, spermatogenesis, and virus entry.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Colon Figure 3 Kidney Figure 4 Testis Figure 5 Skin Figure 6 RNA cell line category: Cell line enhanced (BEWO)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • TYRO3
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • TYRO3 protein tyrosine kinase
  • Biological Process
  • Cell adhesion, Host-virus interaction
  • Molecular Function
  • Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase
  • Introduction
  • The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.
  • Alternative Names
  • Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif
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MOR-3735 Rabbit Anti-TYRO3 Recombinant Antibody (clone DS3735AB) WB, IHC, ICC, IP Rabbit IgG
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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