Recombinant Anti-TYRO3 Vesicular Antibody, EV Displayed (VS-0425-YC436) (CAT#: VS-0425-YC436)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• TYRO3

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• TYRO3 protein tyrosine kinase

• Biological Process
• Cell adhesion, Host-virus interaction

• Molecular Function
• Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase

• Introduction
• The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.

• Alternative Names
• Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif

• Gene ID
• 7301

• UniProt ID
• Q06418

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