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Anti-TYRO3 Recombinant Antibody Products

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Anti-TYRO3 Products

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For Research Use Only. Not For Clinical Use.


At Creative Biolabs, we are proud to offer a superior range of anti-TYRO3 recombinant antibody products, meticulously developed to meet the rigorous demands of global research and therapeutic development. Our antibodies provide unparalleled specificity and consistency, empowering scientists worldwide to advance their understanding of TYRO3 and its critical roles in various biological processes.

TYRO3: A Promising Target for Cancer and Neurological Therapies

TYRO3, a member of the TAM (TYRO3, AXL, MER) family of receptor tyrosine kinases, is a key regulator involved in cell proliferation, survival, migration, and immune modulation. Extensive research highlights its significant involvement in various human cancers, where it often promotes tumorigenesis and chemoresistance. Furthermore, TYRO3 plays crucial roles in immunity, phagocytosis, hemostasis, and neuronal health, with its dysregulation linked to conditions like thrombosis and neurodegenerative diseases. Understanding TYRO3 is therefore vital for developing novel treatments across a spectrum of challenging diseases.

Alternative Names

Tyrosine-protein kinase receptor; BYK; Dtk; RSE; Sky; Tif; Etk-2; Rek; TYRO3 protein tyrosine kinase.

Background

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.

Protein class

Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Peritubular cells, Oligodendrocytes, Leydig cells, Excitatory neurons, Oligodendrocyte precursor cells)

Immune cell specificity

Immune cell enhanced (neutrophil)

Cell line specificity

Cell line enhanced (BEWO)

Interaction

Monomer and homodimer. Interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 (By similarity). Interacts with PIK3R1; this interaction increases PI3-kinase activity (By similarity).

Molecular function

Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase

More Types Infomation

Anti-TYRO3 rAb Products

Our anti-TYRO3 recombinant antibody products are meticulously developed using cutting-edge recombinant DNA technology, ensuring exceptional purity, high binding affinity, and unparalleled batch-to-batch consistency. These antibodies are designed for superior specificity, minimizing non-specific binding and delivering highly reliable and reproducible results for your most demanding experimental applications. Their recombinant production also guarantees a stable and scalable supply, free from the inherent variability of traditional animal-derived antibodies.

Table 1. Featured anti-TYRO3 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
ZG-0488F Mouse Anti-TYRO3 Recombinant Antibody (ZG-0488F) Human Mouse IgG WB, ELISA
ZG-0489F Mouse Anti-TYRO3 Recombinant Antibody (ZG-0489F) Human Mouse IgG IF, ELISA
ZG-0490F Mouse Anti-TYRO3 Recombinant Antibody (ZG-0490F) Human Mouse IgG WB, ELISA
ZG-0491F Mouse Anti-TYRO3 Recombinant Antibody (ZG-0491F) Human Mouse IgG WB, IF, ELISA
HPAB-1528LY Human Anti-TYRO3 Recombinant Antibody (clone 2413) Human Human IgG ELISA

Creative Quality Control

Creative Biolabs implements a stringent quality control process for all anti-TYRO3 recombinant antibodies. Each lot undergoes comprehensive validation to confirm optimal specificity, affinity, and functional activity. We ensure that every product meets the highest standards of purity and performance, providing researchers with confidence in their experimental outcomes and data integrity.

Fig.1 WB analysis. (Creative Biolabs Original)Fig.1 WB analysis of anti-TYRO3 antibody
(Cat# ZG-0488F, Creative Biolabs).

Fig.2 IF analysis. (Creative Biolabs Original)Fig.2 IF analysis of anti-TYRO3 antibody
(Cat# ZG-0489F, Creative Biolabs).

Fig.3 WB analysis. (Creative Biolabs Original)Fig.3 WB analysis of anti-TYRO3 antibody
(Cat# ZG-0490F, Creative Biolabs).

Fig.4 WB analysis. (Creative Biolabs Original)Fig.4 WB analysis of anti-TYRO3 antibody
(Cat# ZG-0491F, Creative Biolabs).

Fig.5 IF analysis. (Creative Biolabs Original)Fig.5 IF analysis of anti-TYRO3 antibody
(Cat# ZG-0491F, Creative Biolabs).

Customer Reviews

Excellent
Pe***a
Rabbit Anti-TYRO3 Recombinant Antibody (clone R65-7S-1) (VS3-FY2128)
The anti-TYRO3 antibody from Creative Biolabs exceeded our expectations. Its performance in our IHC assays was exceptional, showing clear and specific staining without background noise. The consistency across different batches has been remarkable, saving us significant time and resources in our cancer research.
15/Oct/2024
Excellent
Da***d
Mouse Anti-TYRO3 Recombinant Antibody (clone 6D6F10) (VS3-QX1210)
We've been using Creative Biolabs' anti-TYRO3 recombinant antibody for our neurological studies, and the results are incredibly reliable. The high purity and specificity have been crucial for our co-immunoprecipitation experiments, allowing us to confidently identify protein interactions. Their customer support was also very helpful.
28/Nov/2024
Excellent
El***a
Rabbit Anti-TYRO3 Recombinant Antibody (clone DS3735AB) (MOR-3735)
Creative Biolabs' anti-TYRO3 antibody has been a game-changer for our immunology research. We've consistently achieved robust data in diverse applications, from flow cytometry to functional blocking assays. Its reliable performance is truly invaluable for advancing our understanding of immune-related disorders.
20/Jan/2025

rAb Production

Our anti-TYRO3 recombinant antibodies are produced using state-of-the-art mammalian cell expression systems, ensuring proper folding and post-translational modifications crucial for biological activity. This advanced production platform allows for the generation of antibodies with high yields and superior quality, meeting the demands for both research-grade and potential therapeutic development applications.

Featured Anti-TYRO3 Recombinant Antibody Production PlatformsFig.6 Milligram-scale. (Creative Biolabs Original)
Fig.6 Milligram-scale anti-TYRO3 recombinant antibody production.

Fig.7 Gram-scale. (Creative Biolabs Original)Fig.7 Gram-scale anti-TYRO3 recombinant antibody production.

rAb Modalities

Creative Biolabs offers anti-TYRO3 recombinant antibodies in multiple modalities, including various species origins, conjugations, and formats. This versatility ensures that our products are perfectly suited for a wide array of research applications, from basic discovery to preclinical development.

Fig.8 TYRO3 antibody production and modalities. (Creative Biolabs Original)Fig.8 Full-length anti-TYRO3 recombinant antibody production and modalities.

TYRO3-Targeted Drug Information

Table 2. Public drug targeting TYRO3.

Company Research phase Classification Condition
CNRS (Originator)
ElsaLys Biotech (Originator)
Institut Curie (Originator)
Biological Testing Cancer Immunotherapy
Human Monoclonal Antibodies
Cancer
BeiGene
Mirati Therapeutics (Originator)
Phase III Cancer
Cancer, bladder (urothelial carcinoma)
Cancer, breast, metastatic
Cancer, gastrointestinal
Cancer, kidney (renal cell carcinoma, clear cell)
Cancer, liver (hepatocellular carcinoma)
Cancer, lung (non-small cell) (NSCLC)
Cancer, lung (small cell) (SCLC) (extensive)
Cancer, solid tumor
Esophageal carcinoma (squamous cell)
Liposarcoma
Melanoma
Triple negative breast cancer
SignalChem Lifesciences (Originator)
Xuanzhu Biopharma
Xuanzhu Biopharma
Phase I/II Acute myeloid leukemia
Cancer
Cancer, lung (non-small cell) (NSCLC)
Cancer, solid tumor
Myelodysplasia
Betta Pharmaceuticals
Meryx
University North Carolina, Chapel Hill (Originator)
Phase I Acute myeloid leukemia
Cancer
Cancer, lung (non-small cell) (NSCLC)
Cancer, solid tumor
Leukemia
ASLAN Pharmaceuticals
ASLAN Pharmaceuticals
Bristol-Myers Squibb (Originator)
Phase I Cancer, solid tumor
Osteoporosis
Osteoporosis, postmenopausal
Champions Oncology
Daiichi Sankyo (Originator)
Ignyta (Roche)
Roche
Teva (Originator)
IND Filed Cancer Immunotherapy Cancer
Cancer, solid tumor
Kymera Therapeutics (Originator) Preclinical PROTACs (Proteolysis Targeting Chimeras) Cancer
National Health Research Institutes (Originator) Preclinical Cancer
Immunological Disorders
Aucentra Therapeutics (Originator) Preclinical Cancer
Celon Pharma (Originator) Preclinical Cancer
Shanghai Institute of Materia Medica (Originator)
University of Chinese Academy Sciences (Originator)
Preclinical Cancer
Central China Normal University (CCNU) (Originator) Preclinical Cancer

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs is dedicated to providing cutting-edge antibody solutions to accelerate your scientific endeavors. Our expert team is ready to assist you in selecting the ideal anti-TYRO3 recombinant antibody for your specific research needs. We invite you to explore our comprehensive portfolio and contact us today to discuss how our products can empower your next breakthrough.

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