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CCL20

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For Research Use Only. Not For Clinical Use.


Background

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene.
Predicted location

Secreted

Single cell type specificity

Group enriched (Basal respiratory cells, Club cells)

Immune cell specificity

Immune cell enhanced (MAIT T-cell)

Cell line specificity

Cell line enhanced (GAMG, Hep G2, NB-4)

Molecular function

Antibiotic, Antimicrobial, Cytokine

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