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CCNA2
Anti-CCNA2 Recombinant Antibody Products
- PE-B*40:01/Human CCNA2 (YHEDIHTYL) MHC Tetramer (MHC-LC4366)
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- Class: Class I
- Antigen: CCNA2
- Antigen Species: Human
- Peptide: YHEDIHTYL
- Conjugate: PE
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- Mouse Anti-CCNA2 Recombinant Antibody (clone N0-E3) (MRO-0408-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IF, IHC
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- Rabbit Anti-CCNA2 Recombinant Antibody (clone CBACN-161) (MRO-0409-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC
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- AbPlus™ Anti-Ccna2 Magnetic Beads (VS-0724-YC1313) (VS-0724-YC1313)
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- Target: Ccna2
- Target Species: Mouse
- Application: IP, Protein Purification
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- AbPlus™ Anti-CCNA2 Magnetic Beads (VS-0724-YC1370) (VS-0724-YC1370)
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- Target: CCNA2
- Target Species: Human
- Application: IP, Protein Purification
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- Rabbit Anti-CCNA2 Polyclonal Antibody (MRO-1797-CN) (MRO-1797-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-F, IHC-P, ICC, IF, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, IHC, IF, ELISA
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- Mouse Anti-NHP CCNA2 Recombinant Antibody (clone E23.1) (VS-1024-XY145)
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- Species Reactivity: Bovine, Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG2a
- Application: WB, IHC, IF, IP
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- Anti-CCNA2 Immunohistochemistry Kit (VS-0325-XY333)
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- Species Reactivity: Human, Mouse, Rat
- Target: CCNA2
- Application: IHC
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- Rabbit Anti-CCNA2 Recombinant Antibody (VS13-YC146) (VS13-YC146)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC-P
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For Research Use Only. Not For Clinical Use.
CCNA2 (Cyclin A2) is a Protein Coding gene. Diseases associated with CCNA2 include Splenic Diffuse Red Pulp Small B-Cell Lymphoma and Valproate Embryopathy. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Signaling events mediated by PRL. Gene Ontology (GO) annotations related to this gene include protein kinase binding. An important paralog of this gene is CCNA1.
Protein class
Cancer-related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Erythroid cells, Extravillous trophoblasts, Cytotrophoblasts, Plasma cells)
Immune cell specificity
Immune cell enhanced (T-reg)
Cell line specificity
Low cell line specificity
Interaction
Interacts with the CDK1 and CDK2 protein kinases to form serine/threonine kinase holoenzyme complexes (PubMed:1312467, PubMed:7630397, PubMed:8684460, PubMed:8756328). Interacts with CDK1 (hyperphosphorylated form in G1 and underphosphorylated forms in S and G2) (PubMed:1312467). Interacts with CDK2; the interaction increases from G1 to G2 (PubMed:1312467). Interacts (associated with CDK2 but not with CDK1) with SCAPER; regulates the activity of CCNA2/CDK2 by transiently maintaining CCNA2 in the cytoplasm (PubMed:17698606). Forms a ternary complex with CDK2 and CDKN1B; CDKN1B inhibits the kinase activity of CDK2 through conformational rearrangements (PubMed:8684460). Interacts with INCA1 (PubMed:21540187). (Microbial infection) Interacts with human cytomegalovirus protein UL32.
Molecular function
Cyclin
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