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CCND3

Anti-CCND3 Products

Rabbit Anti-CCND3 Recombinant Antibody (clone CBACN-165) (MRO-0414-CN)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, FC
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Mouse Anti-CCND3 Recombinant Antibody (ZG-0448F) (ZG-0448F)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: WB, ELISA
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Mouse Anti-CCND3 Recombinant Antibody (clone DCS2.2) (ZG-0793F)
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IP, IHC
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Rabbit Anti-CCND3 Recombinant Antibody (VS3-CJ865) (VS3-CJ865)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, ICC, IF, FC
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AbPlus™ Anti-CCND3 Magnetic Beads (DCS2.2) (VS-0424-XY46)
- Target: CCND3
- Target Species: Human, Mouse, Rat
- Application: IP, Protein Purification
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AbPlus™ Anti-CCND3 Magnetic Beads (VS-0724-YC1228) (VS-0724-YC1228)
- Target: CCND3
- Target Species: Human
- Application: IP, Protein Purification
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Mouse Anti-CCND3 Recombinant Antibody (clone 7I5) (MOB-0111CT)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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Mouse Anti-CCND3 Recombinant Antibody (clone CBL926) (NEUT-265CQ)
- Species Reactivity: Human, Monkey, Mouse, Rat
- Type: Mouse IgG1
- Application: FC, IF, IHC, IP, WB, Neut
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Mouse Anti-NHP CCND3 Recombinant Antibody (clone DCS-22) (VS-1024-XY149)
- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG1, kappa
- Application: WB, IHC, IP
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Anti-CCND3 (clone W24V166) Recombinant Antibody Coupled Liposome (VS-1024-FY167) (VS-1024-FY167)
- Antibody Host: Mouse
- Antibody Reactivity: Human
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Mouse Anti-CCND3 Recombinant Antibody (clone CBL106HM) (VS7-HM316)
- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: WB, ELISA
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Anti-CCND3 Immunohistochemistry Kit (VS-0325-XY336)
- Species Reactivity: Human, Mouse, Rat
- Target: CCND3
- Application: IHC
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Rabbit Anti-CCND3 Recombinant Antibody (VS13-YC148) (VS13-YC148)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, ICC, IF
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Anti-Mouse CCND3 Immunohistochemistry Kit (VS-0525-XY1089)
- Species Reactivity: Human, Mouse, Rat
- Target: CCND3
- Application: IHC
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Hi-Affi™ Rabbit Anti-CCND3 Recombinant Antibody (clone DS516AB) (MOR-0516)
- Derivation: Phage display library screening
- Species Reactivity: Human, Predicted to work with: Mouse, Rat, Cow
- Type: Rabbit IgG
- Application: FC, IHC-P, WB
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For Research Use Only. Not For Clinical Use.

Cyclin D3 is a critical modulator of the androgen response, whose deregulation may foster unchecked AR activity in prostate cancer.

Protein class

Cancer-related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (NK-cells, Syncytiotrophoblasts)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (MOLT-4, REH)

Interaction

Interacts with the CDK4 and CDK6 protein kinases to form a serine/threonine kinase holoenzyme complex (PubMed:9106657, PubMed:19237555, PubMed:8114739). The cyclin subunit imparts substrate specificity to the complex (PubMed:8114739). Interacts with ATF5 (PubMed:15358120). Interacts with EIF3K (PubMed:15327989). Component of the ternary complex cyclin D/CDK4/CDKN1B required for nuclear translocation and modulation of CDK4-mediated kinase activity (PubMed:16782892). Can form similar complexes with either CDKN1A or CDKN2A (PubMed:9106657, PubMed:16782892).

Molecular function

Cyclin

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Related Signaling Pathways

Hedgehog Signaling Pathway