+ Filter
Loading...
Custom Services order now ship next day

Anti-CD3 Recombinant Antibody Products

Creative Biolabs is dedicated to speeding up research and discovery of target CD3 by providing high-quality, cutting-edge recombinant antibodies.

CD3: A Prominent Target in Inflammatory Disease

CD3 is a key component of the T-cell receptor complex and is involved in T-cell activation and immune response. In cancer immunotherapy, targeting CD3 can help stimulate the immune system to recognize and attack cancer cells. In autoimmune diseases, modulating CD3 activity can potentially regulate the overactive immune response. This approach aims to restore immune balance and reduce tissue damage. Furthermore, the target CD3 provides valuable insights for the development of novel therapeutic strategies and the improvement of existing treatments.

Anti-CD3 Recombinant Antibody Products

We offer high-quality and top-notch antibody products to meet the research demands of a wide range of research personnel regarding the target CD3 and its functions.

Cat. No. Product Name Target Species Host Species Applications
HPAB-1909LY Human Anti-CD3 Recombinant Antibody (HPAB-1909LY) Human Human ELISA; FC
HPAB-0543-WJ Mouse Anti-CD3 Recombinant Antibody (clone YTH 12.5) Human Rat ELISA; FC
HPAB-0546-WJ Human Anti-CD3 Recombinant Antibody (clone HuM291) Human Human Inhib, FC
HPAB-0441-YJ Mouse Anti-CD3 Recombinant Antibody (clone m3E3) Human Mouse ELISA; FC
HPAB-1181WJ Human Anti-CD3 Recombinant Antibody (clone CBLC-007) Human Human ELISA

Creative Quality Control

To meet the demands of our customers, during the production process of antibody products, we have established a series of strict quality management systems to ensure the high quality of the products.

Fig.1 SDS-PAGE analysis of HPAB-M0467-YC-S(P). (Creative Biolabs Original)Fig.1 SDS-PAGE analysis of anti-CD3 antibody
(Cat# HPAB-M0467-YC-S(P), Creative Biolabs).

Fig.2 SEC-HPLC analysis of HPAB-M0467-YC-S(P). (Creative Biolabs Original)Fig.2 SEC-HPLC analysis of anti-CD3 antibody
(Cat# HPAB-M0467-YC-S(P), Creative Biolabs).

Fig.3 WB analysis of HPAB-M0467-YC-S(P). (Creative Biolabs Original)Fig.3 WB analysis of anti-CD3 antibody
(Cat# HPAB-M0467-YC-S(P), Creative Biolabs).

Fig.4 FC analysis of HPAB-M0467-YC-S(P). (Creative Biolabs Original)Fig.4 FC analysis of Jurkat cells incubated with anti-CD3 antibody
(Cat# HPAB-M0467-YC-S(P)).

Customer Reviews

Excellent
De**s
Human Anti-CD3 Recombinant Antibody (clone UCHT-1); scFv Fragment (Cat#: HPAB-M0467-YC-S(P))
This anti-CD3 recombinant human antibody (scFv fragment) was utilized to examine its binding to Jurkat cells. Based on the suggested experimental procedure, we detected outstanding positive effects after incubation.
9/Feb/2024 1 Likes
Excellent
Ai**n
Human Anti-CD3 Recombinant Antibody (Cat#: HPAB-1909LY)
The specificity of this antibody is outstanding. In experiments, it can precisely recognize and bind to the CD3 target with almost no non-specific binding, which provides an accurate and reliable data basis for my research. For example, in flow cytometry analysis of cells, it can clearly distinguish the target cell population, and the results are very clear and definite.
14/Sep/2023 3 Likes
Excellent
Can**ce
Mouse Anti-CD3 Recombinant Antibody (clone YTH 12.5) (Cat#: HPAB-0543-WJ)
This mouse anti-CD3 recombinant antibody was purchased to evaluate its binding to protein human CD3 in ELISA assays. It is really impressive. The specificity is remarkable, precisely targeting CD3 with no off-target binding. Also, its stability is excellent, allowing for reliable storage and use.
23/Apr/2024 2 Likes

Anti-CD3 Recombinant Antibody Production

We offer one-stop services ranging from gene synthesis to the production of high-quality recombinant antibodies. Based on this, we are capable of providing customers with superior antibody production services.

Fig.5 Milligram-scale anti-CD3 recombinant antibody production. (Creative Biolabs Original)Fig.5 Milligram-scale recombinant antibody production.

Fig.6 Gram-scale anti-CD3 recombinant antibody production. (Creative Biolabs Original)Fig.6 Gram-scale recombinant antibody production

Anti-CD3 Recombinant Antibody Modalities

Creative Biolabs is dedicated to offering researchers the most comprehensive and state-of-the-art high-quality recombinant antibodies in various formats. The antibody formats encompass, including full length, Fab, scFv, scFv-Fc, sc-Fab, and so on.

Fig.7 Full Length Anti-CD3 Recombinant Antibody Production and Modalities. (Creative Biolabs Original)Fig.7 Full Length Anti-CD3 Recombinant Antibody Production and Modalities

Alternative Names

Cluster of differentiation 3

Background

In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain, and CD3 molecules together comprise the TCR complex.

Drug Information Targeting CD3

Table 1. Therapeutic approaches targeting CD3 in clinical development.

Research phase Company Classification Indications Details
Launched - 2018 Amgen KK Bispecific Antibody
Cancer Immunotherapy
Precursor B-cell lymphocytic leukemia Bl**m*b is a CD3-directed bispecific antibody used in the treatment of Precursor B-cell lymphocytic leukemia.
Launched - 2023 Pfizer Bispecific Antibody
Cancer Immunotherapy
Human Monoclonal Antibody
Multiple myeloma E**ta*b is a CD3-directed human monoclonal antibody used in the treatment of Multiple myeloma.
Launched - 2023 Genmab Bispecific Antibody
Cancer Immunotherapy
Lymphoma E**t*mab is a bispecific antibody that targets CD3 and is applicable for the treatment of Lymphoma.
Registered - 2023 Roche Monoclonal Antibody Diffuse large B-cell Lymphoma G**ta*ab is a monoclonal antibody that targets CD3 and is applicable for the treatment of Diffuse large B-cell Lymphoma.
Launched - 1993 Janssen Cancer Immunotherapy
Murine Monoclonal Antibody
Transplant rejection M**onab-CD3 is an antibody aimed at CD3 and can be used to alleviate organ rejection reactions.
Launched - 2022 Immunocore TCR-Like Antibody Melanoma T**taf*sp is an antibody aimed at CD3 and can be utilized for the treatment of Melanoma.
Launched - 2022 Janssen Bispecific Antibody
Cancer Immunotherapy
Humanized Monoclonal Antibody
Multiple myeloma T**tamab is a humanized monoclonal antibody targeting CD3 and is capable of being used for the treatment of Multiple myeloma.
Launched - 2023 Sanofi Humanized Monoclonal Antibody Diabetes type 1 T**z*mab is a humanized monoclonal antibody targeting CD3 and is capable of being used for the treatment of Diabetes type 1.
Registered - 2023 Janssen Bispecific Antibody
Cancer Immunotherapy
Humanized Monoclonal Antibody
Multiple myeloma T**et*mab is a humanized monoclonal antibody that targets CD3 and is applicable for the treatment of Multiple myeloma.
Registered - 2024 Amgen Bispecific Antibody
Cancer Immunotherapy
Cancer T**ta*ab is a CD3-directed bispecific antibody used in the treatment of cancer.
Pre-Registered Regeneron Bispecific Antibody
Cancer Immunotherapy
Multiple myeloma L**el**mab is a bispecific antibody aimed at CD3 and can be used in the treatment of multiple myeloma.
Pre-Registered Regeneron Bispecific Antibody
Cancer Immunotherapy
Human Monoclonal Antibody
Diffuse large B-cell Lymphoma O**ext*mab is an antibody aimed at CD3 and can be utilized for the treatment of Diffuse large B-cell Lymphoma.
Phase III Bristol-Myers Squibb Bispecific Antibody
Cancer Immunotherapy
Humanized Monoclonal Antibody
Multiple myeloma A**uc**mab is a humanized monoclonal antibody targeting CD3 and is capable of being used for the treatment of Multiple myeloma.
Phase III Immunocore Bispecific Antibody
Cancer Immunotherapy
Melanoma B**ta*sp is a bispecific antibody targeting CD3 and is capable of being used for the treatment of Melanoma.
Phase III Tolerx Humanized Monoclonal Antibody Diabetes type 1 O**iz*mab is an antibody aimed at CD3 and is available for the treatment of Diabetes type 1.
Phase III AbbVie Bispecific Antibody
Cancer Immunotherapy
Multiple myeloma T*B-383* is a CD3-directed human monoclonal antibody used in the treatment of Multiple myeloma.
Phase I/II Boehringer Ingelheim Bispecific Antibody
Cancer Immunotherapy
Carcinoma B*-764532 is an antibody aimed at CD3 and is available for the treatment of Carcinoma.
Phase II Light Chain Bioscience Cancer Immunotherapy
Human Monoclonal Antibody
Crohn's disease F**lu*ab is a CD3-directed human monoclonal antibody used in the treatment of Crohn's disease.
Phase II Biocon Chimeric Monoclonal Antibody Transplant rejection q-*3 is a chimeric monoclonal antibody aimed at CD3 and can be used to alleviate organ rejection reactions.
Phase II Tolera Therapeutics Murine Monoclonal Antibody Transplant rejection T**-101 is a murine monoclonal antibody antibody that targets CD3 and is applicable for the treatment of Transplant rejection.
Phase II PDL BioPharma Humanized Monoclonal Antibody Crohn's disease V***iz*mab is a humanized monoclonal antibody that targets CD3 and is applicable for the treatment of Crohn's disease.

For more information on anti-CD3 recombinant antibody products, please do not hesitate to contact us. We hope to establish a beneficial collaboration with you.

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

For Research Use Only. Not For Clinical Use.

  • 0
  • 0
Cart
    Go to compare

    Go to compare