Anti-CDK2 Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.

Creative Biolabs is at the forefront of oncology and cell cycle research. Our elite selection of anti-CDK2 recombinant antibodies (rAbs) have been optimized for maximum performance and value. CDK2, or Cyclin-Dependent Kinase 2, is a crucial regulator of the G1/S and G2/M transitions during cell proliferation. As an essential cell cycle kinase, CDK2 is an attractive target in cancer, and our high-quality antibodies are an indispensable tool for examining its role in cell cycle progression, genome stability, and the development of new CDK inhibitors.

CDK2: The Key Kinase for G1/S Transition

CDK2 (cyclin dependent kinase 2) is a serine/threonine protein kinase that plays a key role in regulating the cell cycle. The kinase’s activity is tightly regulated through its association with cyclins. CDK2 primarily binds to two major cyclins: Cyclin E, which promotes the G1/S transition, and Cyclin A2, which drives S-phase progression and entry into mitosis. Once activated, CDK2 can phosphorylate the retinoblastoma protein (Rb) and other substrates to override cell cycle checkpoints, allowing the cell to enter DNA replication. This kinase was once considered an essential cancer target, but its inhibition is complicated by functional redundancy with CDK1. Nevertheless, CDK2’s importance in proliferation, and its frequent dysregulation in tumors, have kept it in the spotlight for research and therapeutic development.

Alternative Names

Cyclin-dependent kinase 2; EC 2.7.11.22; Cell division protein kinase 2; p33 protein kinase; CDK2; CDKN2

Background

Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases.

Anti-CDK2 rAb Products

Our premium anti-CDK2 recombinant antibodies have been engineered to ensure specificity and exceptional performance. We offer a total CDK2 antibody to monitor its levels in the cell, as well as phospho-specific antibodies (e.g., pThr160) that can be used to track its activation status. Optimized for applications such as Western Blot, IHC, and kinase assays, our rAbs are a top choice for in-depth cell cycle research.
Table 1. Featured anti-CDK2 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs is dedicated to uncompromising scientific rigor. The manufacturing of our anti-CDK2 recombinant antibodies is subject to strict quality assurance protocols. Each lot is tested for purity and specificity to other CDKs, as well as performance across validated cell models, so you can be confident you are getting a high-quality reagent.

Customer Reviews

rAb Production

Creative Biolabs serves the specialized needs of researchers in oncology and cell cycle research with our advanced rAb production platforms. Our anti-CDK2 recombinant antibodies are expressed in optimized systems, guaranteeing they recognize the native kinase and that you are getting the most specific and active tool possible.

Featured Anti-CDK2 Recombinant Antibody Production Platforms
Fig.3 Milligram-scale anti-CDK2 recombinant antibody production.

Fig.4 Gram-scale anti-CDK2 recombinant antibody production.

rAb Modalities

Creative Biolabs empowers scientific discovery through cutting-edge antibody technology. Our anti-CDK2 recombinant antibodies are available in a range of customizable modalities, including phospho-specific clones to fit your experimental needs.

Fig.5 Full-length anti-CDK2 recombinant antibody production and modalities.

Probe the G1/S transition with the help of Creative Biolabs’ high-quality anti-CDK2 recombinant antibodies. Our portfolio is designed to deliver the validation and specificity you need for cell cycle kinase research. Put your research on a solid foundation with antibodies from Creative Biolabs. Contact our scientific team today.