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CHD4

Anti-CHD4 Products
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- Species Reactivity: Human
- Type: Human IgG
- Application: IF, ELISA, IP-MS
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- Species Reactivity: Human
- Application: FC, IHC-P, WB
- Rabbit Anti-CHD4 Recombinant Antibody (clone JA33-40) (MRO-0358-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, IP
- Mouse Anti-CHD4 Recombinant Antibody (VS4-WK107) (VS4-WK107)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, WB, IP
- AbPlus™ Anti-CHD4 Magnetic Beads (D406) (VS-0424-XY64)
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- Target: CHD4
- Target Species: Human
- Application: IP-MS, Protein Purification
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- Species Reactivity: Human
- Type: Human Fab
- Application: IP, IF, ELISA, IP-MS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Anti-CHD4 Immunohistochemistry Kit (VS-0325-XY444)
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- Species Reactivity: Human, Mouse, Rat
- Target: CHD4
- Application: IHC
- Anti-Mouse CHD4 Immunohistochemistry Kit (VS-0525-XY1427)
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- Species Reactivity: Human, Mouse
- Target: CHD4
- Application: IHC
- Anti-Human CHD4 Immunohistochemistry Kit (VS-0525-XY1426)
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- Species Reactivity: Human
- Target: CHD4
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, FC
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For Research Use Only. Not For Clinical Use.
Background
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.