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COL4A1
Anti-COL4A1 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
COL4A1 (Collagen Type IV Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL4A1 include Retinal Arteries, Tortuosity Of and Schizencephaly. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include extracellular matrix structural constituent and extracellular matrix constituent conferring elasticity. An important paralog of this gene is COL4A5.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Sertoli cells, Smooth muscle cells, Adipocytes, Endothelial cells, Endometrial stromal cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (ASC diff, EFO-21, TIME)
Interaction
There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. Interacts with EFEMP2 (By similarity).
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