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CTNND1
Anti-CTNND1 Recombinant Antibody Products
- Rabbit Anti-CTNND1 Recombinant Antibody (VS3-FY2680) (VS3-FY2680)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, IP
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For Research Use Only. Not For Clinical Use.
CTNND1 (Catenin Delta 1) is a Protein Coding gene. Diseases associated with CTNND1 include Blepharocheilodontic Syndrome 2 and Blepharocheilodontic Syndrome 1. Among its related pathways are N-cadherin signaling events and PAK Pathway. Gene Ontology (GO) annotations related to this gene include binding and receptor binding. An important paralog of this gene is ARVCF.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Distal enterocytes)
Immune cell specificity
Group enriched (intermediate monocyte, myeloid DC, non-classical monocyte, classical monocyte)
Cell line specificity
Low cell line specificity
Interaction
Belongs to a multiprotein cell-cell adhesion complex that also contains E-cadherin/CDH1, alpha-catenin/CTNNA1, beta-catenin/CTNNB1, and gamma-catenin/JUP (PubMed:20371349, PubMed:15240885). Component of a cadherin:catenin adhesion complex composed of at least of CDH26, beta-catenin/CTNNB1, alpha-catenin/CTNNA1 and p120 catenin/CTNND1 (PubMed:28051089). Binds to the C-terminal fragment of PSEN1 and mutually competes for CDH1. Interacts with ZBTB33 (PubMed:10207085). Interacts with GLIS2 (PubMed:17344476). Interacts with FER (PubMed:7623846). Interacts with NANOS1 (via N-terminal region) (PubMed:17047063). Interacts (via N-terminus) with GNA12; the interaction regulates CDH1-mediated cell-cell adhesion (PubMed:15240885). Interacts with GNA13 (PubMed:15240885). Interacts with CCDC85B (PubMed:25009281). Interacts with PLPP3; negatively regulates the PLPP3-mediated stabilization of CTNNB1 (PubMed:20123964).
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