Rabbit Anti-CTNND1 Recombinant Antibody (VS3-FY2680)
CAT#: VS3-FY2680
The anti-CTNND1 antibody has been genetically engineered to specifically target human delta 1 Catenin protein. It shows capability of cross-reacting with mouse and rat. This monoclonal antibody proves valuable in disease research related to Blepharocheilodontic Syndrome 2 and Blepharocheilodontic Syndrome 1.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15955/if_selected.jpg
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Catenin delta 1 of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC, IP
- Conjugate
- Unconjugated, FITC
- Related Disease
- Blepharocheilodontic Syndrome 2 and Blepharocheilodontic Syndrome 1
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunoprecipitation: 1/20
Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- Catenin Delta 1; Catenin (Cadherin-Associated Protein), Delta 1; Cadherin-Associated Src Substrate; P120 Catenin; P120(CAS); P120(CTN); CAS; Catenin Delta-1
- Gene ID
- 1500
- UniProt ID
- O60716
- Sequence Similarities
- Belongs to the beta-catenin family.
- Cellular Localization
- Cell junction, adherens junction
Cytoplasm
Nucleus
Cell membrane
- Post Translation Modifications
- Phosphorylated by FER and other protein-tyrosine kinases.
Phosphorylated at Ser-288 by PAK5.
Dephosphorylated by PTPRJ.
Glycosylation at Asn641
Ubiquitination at Lys710
Modification sites at PhosphoSitePlus
Glycosylation from Gly
Glycosylation from GlyGen 2 sites, 3 N-linked glycans (1 site), 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001078927.1; NP_001078928.1; NP_001078929.1; NP_001078930.1; NP_001078931.1
- Function
- Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed:14610055, 20371349).
Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "CTNND1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3971z | Mouse Anti-CTNND1 Recombinant Antibody (clone 43H7) | WB, IP, IF | Mouse IgG1, κ |
| MOB-0047CT | Recombinant Mouse anti-Human CTNND1 Monoclonal antibody (3345D7b) | Dot, ICC, WB | |
| VS3-CJ159 | Mouse Anti-CTNND1 Recombinant Antibody (VS3-CJ159) | WB, IHC | Mouse IgG |
| VS3-WK2022 | Rabbit Anti-CTNND1 (pS268) Recombinant Antibody (clone R06-0H8) | WB | Rabbit IgG |
| VS3-WK2023 | Rabbit Anti-CTNND1 (pT916) Recombinant Antibody (clone R07-5A6) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0862 | Hi-Affi™ Rabbit Anti-CTNND1 Recombinant Antibody (clone DS862AB) | ICC, IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1773 | Anti-CTNND1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1774 | Anti-Mouse CTNND1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1775 | Anti-Rat CTNND1 Immunohistochemistry Kit | IHC |
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