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GATA3
Loading...Anti-GATA3 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, ICC, IF, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
Compare
- Anti-Mouse GATA3 Immunohistochemistry Kit (VS-0525-XY2743)
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- Species Reactivity: Human, Mouse
- Target: GATA3
- Application: IHC
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- Anti-GATA3 Immunohistochemistry Kit (VS-0525-XY2742)
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- Species Reactivity: Human
- Target: GATA3
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Extravillous trophoblasts, Cytotrophoblasts, Breast glandular cells, Suprabasal keratinocytes)
Immune cell specificity
Group enriched (T-reg, memory CD4 T-cell, NK-cell, memory CD8 T-cell, MAIT T-cell, naive CD4 T-cell, gdT-cell, naive CD8 T-cell)
Cell line specificity
Cell line enhanced (BEWO, MCF7, RT4, SH-SY5Y, T-47d)
Interaction
Interacts with TBX21 ('Tyr-530' phosphorylated form).
Molecular function
Activator, DNA-binding
More Types Infomation
Related Diseases
Inflammatory Bowel Diseases