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HK2

Anti-HK2 Products
- Mouse Anti-HK2 Recombinant Antibody (HPAB-0618-WJ) (HPAB-0618-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IF
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
- Mouse Anti-HK2 Recombinant Antibody (VS4-WK220) (VS4-WK220)
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- Derivation: Mouse
- Species Reactivity: Human, Pig, Mouse, Rat
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-HK2 Recombinant Antibody (VS3-FY2736) (VS3-FY2736)
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- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human, Rat, Mouse, Monkey
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human, Mouse, Rat, Pig
- Type: Mouse IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
- Mouse Anti-HK2 Recombinant Antibody (VS3-CJ1032) (VS3-CJ1032)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC-P
- Mouse Anti-HK2 Recombinant Antibody (clone 3D3) (VS3-XY808)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, FC, ICC
- Rabbit Anti-NHP HK2 Recombinant Antibody (VS-1024-XY249) (VS-1024-XY249)
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- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Rabbit IgG
- Application: WB
- Mouse Anti-HK2 Recombinant Antibody; Fab Fragment (HPAB-0618-WJ-F(E)) (HPAB-0618-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-HK2 Recombinant Antibody; scFv Fragment (HPAB-0618-WJ-S(P)) (HPAB-0618-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P, IF
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Anti-HK2 Immunohistochemistry Kit (VS-0325-XY1027)
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- Species Reactivity: Human, Mouse, Rat
- Target: HK2
- Application: IHC
- Mouse Anti-HK2 Monoclonal Antibody (VS7-0425-WR66) (VS7-0425-WR66)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, FC, ELISA
- Anti-Human HK2 Immunohistochemistry Kit (VS-0525-XY3162)
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- Species Reactivity: Human
- Target: HK2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]

Protein class
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Distal enterocytes, Paneth cells, Early spermatids)
Immune cell specificity
Immune cell enhanced (eosinophil)
Cell line specificity
Cell line enhanced (U-87 MG)
Interaction
Monomer (By similarity). Interacts with TIGAR; the interaction increases hexokinase activity in a hypoxia- and HIF1A-dependent manner (PubMed:23185017).
Molecular function
Allosteric enzyme, Kinase, Transferase
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