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LAMP2
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- Recombinant Mouse Anti-LAMP2 Monoclonal Antibody (C9-9) (MRO-0917-CN)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2b
- Application: WB, IF, IHC, FC
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- Rabbit Anti-LAMP2 Polyclonal Antibody (MRO-2007-CN) (MRO-2007-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC
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- Mouse Anti-LAMP2 Recombinant Antibody (clone C9-9) (VS3-XY1002)
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- Type: Mouse IgG2b
- Application: WB, ICC
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- AbPlus™ Anti-LAMP2 Magnetic Beads (VS-0724-YC1043) (VS-0724-YC1043)
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- Target: LAMP2
- Target Species: Human
- Application: IP, Protein Purification
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, FC, IHC
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- Mouse Anti-NHP LAMP2 Recombinant Antibody (clone H4B4) (VS-1024-XY302)
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- Species Reactivity: Human, Mouse, Non-human primate
- Type: Mouse IgG2b
- Application: WB, IF, FC
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- Anti-LAMP2 Immunohistochemistry Kit (VS-0325-XY1225)
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- Species Reactivity: Human, Mouse
- Target: LAMP2
- Application: IHC
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- Rabbit Anti-LAMP2 Recombinant Antibody (VS13-YC646) (VS13-YC646)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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- Anti-Mouse LAMP2 Immunohistochemistry Kit (VS-0525-XY3941)
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- Species Reactivity: Human, Mouse, Rat
- Target: LAMP2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and Atrial Standstill 1. Among its related pathways are Phagosome and Innate Immune System. Gene Ontology (GO) annotations related to this gene include enzyme binding and protein domain specific binding. An important paralog of this gene is LAMP1.
Protein class
CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Syncytiotrophoblasts)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Low cell line specificity
Interaction
Monomer (PubMed:18644871, 25342746). Homodimer (PubMed:25342746). Homotrimer (PubMed:25342746). Forms large homooligomers (PubMed:18644871). Interacts (via its cytoplasmic region) with HSPA8 (PubMed:25342746). Interacts with HSP90 in the lysosome lumen; this enhances LAMP2 stability (By similarity). Interacts with MLLT11 (PubMed:24880125). Interacts with ABCB9 (PubMed:22641697). Interacts with FURIN (PubMed:32295904). (Microbial infection) Interacts with mumps virus protein F; this interaction promotes protein F cleavage by FURIN.
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