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MAPK11
Loading...Anti-MAPK11 Products
- Mouse Anti-MAPK11 Recombinant Antibody (clone 4H6H6) (VS3-XY1039)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants.
Protein class
Enzymes, FDA approved drug targets, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Adipocytes, Endothelial cells, Hepatic stellate cells, Astrocytes, Excitatory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Interacts with HDAC3 and DUSP16.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
Related Signaling Pathways
FcεR1 Signaling Pathway
TCR Signaling Pathway
Related Diseases
Maturity Onset Diabetes of the Young