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Matrix protein 2
Tetramer Products
Soluble T Cell Receptor Products
Recombinant Antibody Products
Functional Antibody Products
Formats
Anti-Matrix protein 2 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Influenza a virus
- Type: IgG
- Application: WB, ELISA, FuncS
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- Recombinant Mouse Anti-M2e Antibody scFv Fragment (PABX-140-S (P)) (PABX-140-S (P))
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- Derivation: Mouse
- Species Reactivity: Influenza a virus
- Type: scFv
- Application: WB, ELISA, FuncS
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- APC-A*02:01/M2 (LMLGEFLKL) MHC Tetramer (MHC-CN0173)
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- Class: Class I
- Antigen: M2
- Peptide: LMLGEFLKL
- Conjugate: APC
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- Human Anti-M2E Recombinant Antibody (HPAB-1299-FY) (HPAB-1299-FY)
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- Species Reactivity: IAV
- Type: Human IgG
- Application: ELISA
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- Recombinant Humanized Anti-M2 protein Antibody (h14C2) (HPAB-AP732-YC)
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- Derivation: Humanized
- Species Reactivity: IAV
- Type: Humanized IgG
- Application: FC, WB, ELISA, FC, Inhib
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- Recombinant Human Anti-M2e Antibody (8I10) (HPAB-0980WJ)
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- Species Reactivity: Influenza virus
- Type: Human IgG
- Application: ELISA, FC
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- PE-A*02:01/M2 (LMLGEFLKL) MHC Tetramer (MHC-CN0174)
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- Class: Class I
- Antigen: M2
- Peptide: LMLGEFLKL
- Conjugate: PE
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- Human Anti-M2E Recombinant Antibody (HPAB-1300-FY) (HPAB-1300-FY)
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- Species Reactivity: IAV
- Type: Human IgG
- Application: ELISA
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- Recombinant Human Anti-M2e Antibody (23K12) (HPAB-0981WJ)
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- Species Reactivity: Influenza virus
- Type: Human IgG
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody (3241_G23) (HPAB-0982WJ)
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- Species Reactivity: Influenza virus
- Type: Human IgG
- Application: ELISA, FC
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
- Conjugate: FITC
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
- Conjugate: PE
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
- Conjugate: APC
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
- Conjugate: BV421
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- Recombinant Human Anti-M2e Antibody (3244_I10) (HPAB-0983WJ)
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- Species Reactivity: Influenza virus
- Type: Human IgG
- Application: ELISA, FC
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- Mouse Anti-M2e Antibody, mRNA (PABX-140-mRNA) (PABX-140-mRNA)
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- Species Reactivity: Influenza a virus
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- Mouse Anti-M2 protein Antibody (clone mAb 65), mRNA (PABL-226-mRNA)
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- Species Reactivity: Influenza A virus
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- Recombinant Mouse Anti-Matrix M2 Soluble TCR (TRBV13-2) (KIH) (VS-0622-YF6484)
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- Species Reactivity: Respiratory Syncytial Virus
- Epitope: SYIGSINNI
- MHC: H-2Kd
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- Recombinant Human Anti-M2e Antibody scFv Fragment (3244_I10) (HPAB-0983WJ-S(P))
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- Species Reactivity: Influenza virus
- Type: Human scFv
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody Fab Fragment (3244_I10) (HPAB-0983WJ-F(E))
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- Species Reactivity: Influenza virus
- Type: Human Fab
- Application: ELISA, FC
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- Recombinant Mouse Anti-Matrix M2 Soluble TCR (TRBV13-2) (C-Cys) (VS-0622-YF3776)
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- Species Reactivity: Respiratory Syncytial Virus
- Epitope: SYIGSINNI
- MHC: H-2Kd
Compare
- Recombinant Human Anti-M2e Antibody scFv Fragment (3241_G23) (HPAB-0982WJ-S(P))
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- Species Reactivity: Influenza virus
- Type: Human scFv
- Application: ELISA, FC
Compare
- Recombinant Human Anti-M2e Antibody Fab Fragment (3241_G23) (HPAB-0982WJ-F(E))
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- Species Reactivity: Influenza virus
- Type: Human Fab
- Application: ELISA, FC
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- Mouse Anti-Matrix M2 Recombinant Soluble TCR (TRBV13-2) (scTCR-313ZP-S(P))
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- Species Reactivity: RSV
- Epitope: SYIGSINNI
- MHC: H-2Kd
Compare
- Recombinant Human Anti-M2e Antibody scFv Fragment (23K12) (HPAB-0981WJ-S(P))
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- Species Reactivity: Influenza virus
- Type: Human scFv
- Application: ELISA, FC
Compare
- Recombinant Human Anti-M2e Antibody Fab Fragment (23K12) (HPAB-0981WJ-F(E))
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- Species Reactivity: Influenza virus
- Type: Human Fab
- Application: ELISA, FC
Compare
- Human Anti-M2E Recombinant Antibody; scFv Fragment (HPAB-1300-FY-S(P)) (HPAB-1300-FY-S(P))
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- Species Reactivity: IAV
- Type: Human scFv
- Application: ELISA
Compare
- Recombinant Human Anti-M2e Antibody scFv Fragment (8I10) (HPAB-0980WJ-S(P))
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- Species Reactivity: Influenza virus
- Type: Human scFv
- Application: ELISA, FC
Compare
- Recombinant Human Anti-M2e Antibody Fab Fragment (8I10) (HPAB-0980WJ-F(E))
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- Species Reactivity: Influenza virus
- Type: Human Fab
- Application: ELISA, FC
Compare
- Human Anti-M2E Recombinant Antibody; Fab Fragment (HPAB-1300-FY-F(E)) (HPAB-1300-FY-F(E))
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- Species Reactivity: IAV
- Type: Human Fab
- Application: ELISA
Compare
- Recombinant Humanized Anti-M2 protein Antibody scFv Fragment (h14C2) (HPAB-AP732-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: IAV
- Type: Human scFv
- Application: ELISA, FC, Inhib, WB
Compare
- Recombinant Humanized Anti-M2 protein Antibody Fab Fragment (h14C2) (HPAB-AP732-YC--F(E))
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- Derivation: Humanized
- Species Reactivity: IAV
- Type: Humanized Fab
- Application: ELISA, FC, Inhib, WB
Compare
- Human Anti-M2E Recombinant Antibody; Fab Fragment (HPAB-1299-FY-F(E)) (HPAB-1299-FY-F(E))
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- Species Reactivity: IAV
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-M2E Recombinant Antibody; scFv Fragment (HPAB-1299-FY-S(P)) (HPAB-1299-FY-S(P))
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- Species Reactivity: IAV
- Type: Human scFv
- Application: ELISA
Compare
- Anti-IAV M2 Recombinant Antibody (14C2) (MRO-240CT)
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: IAV
- Application: WB
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- Anti-IAV M2 Recombinant Antibody scFv Fragment (14C2) (MRO-240CT-S(P))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: IAV
- Application: IF, ELISA
Compare
- Anti-IAV M2 Recombinant Antibody Fab Fragment (14C2) (MRO-240CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: IAV
- Application: IF, ELISA
Compare
- Recombinant Mouse Anti-M2e Antibody Fab Fragment (PABX-140-F (E)) (PABX-140-F (E))
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- Derivation: Mouse
- Species Reactivity: Influenza a virus
- Type: Fab
- Application: WB, ELISA, FuncS
Compare
- Human Anti-M2 scFv-Fc Chimera (VS-0325-FY49) (VS-0325-FY49)
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- Species Reactivity: Influenza A virus (IAV)
- Type: Human IgG1, scFv-Fc
- Application: Neut
Compare
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For Research Use Only. Not For Clinical Use.
The M2 protein is a proton-selective ion channel protein, integral in the viral envelope of the influenza A virus. The channel itself is a homotetramer (consists of four identical M2 units), where the units are helices stabilized by two disulfide bonds. It is activated by low pH. M2 protein is encoded on the seventh RNA segment together with the matrix protein M1. Proton conductance by the M2 protein ininfluenza A is essential for viral replication.
The influenza A virus M2 protein is an integral membrane protein that functions as a proton-selective ion channel. It plays a crucial role in the viral replication cycle, particularly in the process of viral uncoating within endosomes. It is essential for maintaining the proper pH balance within the virus during its entry into host cells. The M2 protein is also a target for antiviral drugs, such as amantadine and rimantadine, although resistance to these drugs has become widespread. It is a homotetramer, meaning it is made up of 4 identical M2 protein subunits.