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Matrix protein 2
Loading...Anti-Matrix protein 2 Products
- APC-A*02:01/M2 (LMLGEFLKL) MHC Tetramer (MHC-CN0173)
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- Class: Class I
- Antigen: M2
- Peptide: LMLGEFLKL
- Conjugate: APC
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- Derivation: Mouse
- Species Reactivity: Influenza a virus
- Type: IgG
- Application: WB, ELISA, FuncS
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- Recombinant Mouse Anti-M2e Antibody scFv Fragment (PABX-140-S (P)) (PABX-140-S (P))
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- Derivation: Mouse
- Species Reactivity: Influenza a virus
- Type: scFv
- Application: WB, ELISA, FuncS
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- Human Anti-M2E Recombinant Antibody (HPAB-1299-FY) (HPAB-1299-FY)
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- Species Reactivity: IAV
- Type: Human IgG
- Application: ELISA
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- Mouse Anti-M2e Antibody, mRNA (PABX-140-mRNA) (PABX-140-mRNA)
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- Species Reactivity: Influenza a virus
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- Recombinant Human Anti-M2e Antibody (23K12) (HPAB-0981WJ)
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- Species Reactivity: Influenza virus
- Type: Human IgG
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody (3241_G23) (HPAB-0982WJ)
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- Species Reactivity: Influenza virus
- Type: Human IgG
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody (3244_I10) (HPAB-0983WJ)
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- Species Reactivity: Influenza virus
- Type: Human IgG
- Application: ELISA, FC
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- Human Anti-M2E Recombinant Antibody (HPAB-1300-FY) (HPAB-1300-FY)
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- Species Reactivity: IAV
- Type: Human IgG
- Application: ELISA
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- PE-A*02:01/M2 (LMLGEFLKL) MHC Tetramer (MHC-CN0174)
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- Class: Class I
- Antigen: M2
- Peptide: LMLGEFLKL
- Conjugate: PE
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- Recombinant Humanized Anti-M2 protein Antibody (h14C2) (HPAB-AP732-YC)
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- Derivation: Humanized
- Species Reactivity: IAV
- Type: Humanized IgG
- Application: FC, WB, ELISA, FC, Inhib
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- Mouse Anti-M2 protein Antibody (clone mAb 65), mRNA (PABL-226-mRNA)
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- Species Reactivity: Influenza A virus
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- Recombinant Human Anti-M2e Antibody (8I10) (HPAB-0980WJ)
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- Species Reactivity: Influenza virus
- Type: Human IgG
- Application: ELISA, FC
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
- Conjugate: APC
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
- Conjugate: PE
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
- Conjugate: FITC
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- Class: Class II
- Antigen: Matrix protein 2
- Antigen Species: Respiratory syncytial virus
- Peptide: NYFEWPPHALLVRQ
- Conjugate: BV421
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- Anti-IAV M2 Recombinant Antibody (14C2) (MRO-240CT)
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: IAV
- Application: WB
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- Anti-IAV M2 Recombinant Antibody scFv Fragment (14C2) (MRO-240CT-S(P))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: IAV
- Application: IF, ELISA
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- Anti-IAV M2 Recombinant Antibody Fab Fragment (14C2) (MRO-240CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: IAV
- Application: IF, ELISA
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- Mouse Anti-Matrix M2 Recombinant Soluble TCR (TRBV13-2) (scTCR-313ZP-S(P))
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- Species Reactivity: RSV
- Epitope: SYIGSINNI
- MHC: H-2Kd
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- Recombinant Mouse Anti-Matrix M2 Soluble TCR (TRBV13-2) (C-Cys) (VS-0622-YF3776)
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- Species Reactivity: Respiratory Syncytial Virus
- Epitope: SYIGSINNI
- MHC: H-2Kd
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- Recombinant Mouse Anti-Matrix M2 Soluble TCR (TRBV13-2) (KIH) (VS-0622-YF6484)
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- Species Reactivity: Respiratory Syncytial Virus
- Epitope: SYIGSINNI
- MHC: H-2Kd
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- Recombinant Humanized Anti-M2 protein Antibody scFv Fragment (h14C2) (HPAB-AP732-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: IAV
- Type: Human scFv
- Application: ELISA, FC, Inhib, WB
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- Recombinant Humanized Anti-M2 protein Antibody Fab Fragment (h14C2) (HPAB-AP732-YC--F(E))
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- Derivation: Humanized
- Species Reactivity: IAV
- Type: Humanized Fab
- Application: ELISA, FC, Inhib, WB
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- Human Anti-M2E Recombinant Antibody; Fab Fragment (HPAB-1299-FY-F(E)) (HPAB-1299-FY-F(E))
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- Species Reactivity: IAV
- Type: Human Fab
- Application: ELISA
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- Human Anti-M2E Recombinant Antibody; Fab Fragment (HPAB-1300-FY-F(E)) (HPAB-1300-FY-F(E))
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- Species Reactivity: IAV
- Type: Human Fab
- Application: ELISA
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- Human Anti-M2E Recombinant Antibody; scFv Fragment (HPAB-1299-FY-S(P)) (HPAB-1299-FY-S(P))
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- Species Reactivity: IAV
- Type: Human scFv
- Application: ELISA
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- Human Anti-M2E Recombinant Antibody; scFv Fragment (HPAB-1300-FY-S(P)) (HPAB-1300-FY-S(P))
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- Species Reactivity: IAV
- Type: Human scFv
- Application: ELISA
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- Recombinant Human Anti-M2e Antibody scFv Fragment (8I10) (HPAB-0980WJ-S(P))
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- Species Reactivity: Influenza virus
- Type: Human scFv
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody scFv Fragment (23K12) (HPAB-0981WJ-S(P))
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- Species Reactivity: Influenza virus
- Type: Human scFv
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody scFv Fragment (3241_G23) (HPAB-0982WJ-S(P))
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- Species Reactivity: Influenza virus
- Type: Human scFv
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody scFv Fragment (3244_I10) (HPAB-0983WJ-S(P))
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- Species Reactivity: Influenza virus
- Type: Human scFv
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody Fab Fragment (8I10) (HPAB-0980WJ-F(E))
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- Species Reactivity: Influenza virus
- Type: Human Fab
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody Fab Fragment (23K12) (HPAB-0981WJ-F(E))
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- Species Reactivity: Influenza virus
- Type: Human Fab
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody Fab Fragment (3241_G23) (HPAB-0982WJ-F(E))
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- Species Reactivity: Influenza virus
- Type: Human Fab
- Application: ELISA, FC
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- Recombinant Human Anti-M2e Antibody Fab Fragment (3244_I10) (HPAB-0983WJ-F(E))
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- Species Reactivity: Influenza virus
- Type: Human Fab
- Application: ELISA, FC
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- Recombinant Mouse Anti-M2e Antibody Fab Fragment (PABX-140-F (E)) (PABX-140-F (E))
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- Derivation: Mouse
- Species Reactivity: Influenza a virus
- Type: Fab
- Application: WB, ELISA, FuncS
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- Human Anti-M2 scFv-Fc Chimera (VS-0325-FY49) (VS-0325-FY49)
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- Species Reactivity: Influenza A virus (IAV)
- Type: Human IgG1, scFv-Fc
- Application: Neut
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For Research Use Only. Not For Clinical Use.
Background
The M2 protein is a proton-selective ion channel protein, integral in the viral envelope of the influenza A virus. The channel itself is a homotetramer (consists of four identical M2 units), where the units are helices stabilized by two disulfide bonds. It is activated by low pH. M2 protein is encoded on the seventh RNA segment together with the matrix protein M1. Proton conductance by the M2 protein ininfluenza A is essential for viral replication.
The influenza A virus M2 protein is an integral membrane protein that functions as a proton-selective ion channel. It plays a crucial role in the viral replication cycle, particularly in the process of viral uncoating within endosomes. It is essential for maintaining the proper pH balance within the virus during its entry into host cells. The M2 protein is also a target for antiviral drugs, such as amantadine and rimantadine, although resistance to these drugs has become widespread. It is a homotetramer, meaning it is made up of 4 identical M2 protein subunits.