Enzymes, Metabolic proteins, Plasma proteins, RAS pathway related proteins
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Interacts with SH3MD4. Interacts with SCRIB. Interacts with ARHGEF7 and GIT1. PAK-2p34 interacts with ARHGAP10 (PubMed:15471851, PubMed:16374509, PubMed:18716323, PubMed:19273597). Interacts with RAC1 (PubMed:20696164). (Microbial infection) Interacts with and activated by HIV-1 Nef.
Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase
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For Research Use Only. Not For Clinical Use.