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PRAME

Anti-PRAME Products

APC-A*02:01/Human PRAME P300 (ALYVDSLFFL) MHC Tetramer (MHC-CN0021)
- Class: Class I
- Antigen: PRAME P300
- Antigen Species: Human
- Peptide: ALYVDSLFFL
- Conjugate: APC
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PE-A*02:01/Human PRAME P300 (ALYVDSLFFL) MHC Tetramer (MHC-CN0022)
- Class: Class I
- Antigen: PRAME P300
- Antigen Species: Human
- Peptide: ALYVDSLFFL
- Conjugate: PE
Compare

APC-A*02:01/Human Prame (HLIGLSNLT) MHC Tetramer (MHC-CN0107)
- Class: Class I
- Antigen: Prame
- Antigen Species: Human
- Peptide: HLIGLSNLT
- Conjugate: APC
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PE-A*02:01/Human Prame (HLIGLSNLT) MHC Tetramer (MHC-CN0108)
- Class: Class I
- Antigen: Prame
- Antigen Species: Human
- Peptide: HLIGLSNLT
- Conjugate: PE
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APC-A*02:01/Human Prame (NLTHVLYPV) MHC Tetramer (MHC-CN0207)
- Class: Class I
- Antigen: Prame
- Antigen Species: Human
- Peptide: NLTHVLYPV
- Conjugate: APC
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PE-A*02:01/Human Prame (NLTHVLYPV) MHC Tetramer (MHC-CN0208)
- Class: Class I
- Antigen: Prame
- Antigen Species: Human
- Peptide: NLTHVLYPV
- Conjugate: PE
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Human Anti-PRAME Recombinant Antibody (HPAB-1753LY) (HPAB-1753LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1754LY) (HPAB-1754LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1755LY) (HPAB-1755LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1756LY) (HPAB-1756LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1757LY) (HPAB-1757LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1758LY) (HPAB-1758LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1747LY) (HPAB-1747LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1748LY) (HPAB-1748LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1749LY) (HPAB-1749LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1750LY) (HPAB-1750LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1751LY) (HPAB-1751LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1752LY) (HPAB-1752LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1741LY) (HPAB-1741LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1742LY) (HPAB-1742LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1743LY) (HPAB-1743LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody (HPAB-1744LY) (HPAB-1744LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1745LY) (HPAB-1745LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1746LY) (HPAB-1746LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1735LY) (HPAB-1735LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1736LY) (HPAB-1736LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1737LY) (HPAB-1737LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1738LY) (HPAB-1738LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1739LY) (HPAB-1739LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1740LY) (HPAB-1740LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1729LY) (HPAB-1729LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody (HPAB-1730LY) (HPAB-1730LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
Compare

PE-A*02:01/Human PRAME (ALYVDSLFFL) MHC Tetramer (MHC-LC181)
- Class: Class I
- Antigen: PRAME
- Antigen Species: Human
- Peptide: ALYVDSLFFL
- Conjugate: PE
Compare

APC-A*02:01/Human PRAME (ALYVDSLFFL) MHC Tetramer (MHC-LC182)
- Class: Class I
- Antigen: PRAME
- Antigen Species: Human
- Peptide: ALYVDSLFFL
- Conjugate: APC
Compare

PE-A*02:01/Human PRAME (VLDGLDVLL) MHC Tetramer (MHC-LC183)
- Class: Class I
- Antigen: PRAME
- Antigen Species: Human
- Peptide: VLDGLDVLL
- Conjugate: PE
Compare

APC-A*02:01/Human PRAME (VLDGLDVLL) MHC Tetramer (MHC-LC184)
- Class: Class I
- Antigen: PRAME
- Antigen Species: Human
- Peptide: VLDGLDVLL
- Conjugate: APC
Compare

PE-A*02:01/Human PRAME (SLLQHLIGL) MHC Tetramer (MHC-LC185)
- Class: Class I
- Antigen: PRAME
- Antigen Species: Human
- Peptide: SLLQHLIGL
- Conjugate: PE
Compare

APC-A*02:01/Human PRAME (SLLQHLIGL) MHC Tetramer (MHC-LC186)
- Class: Class I
- Antigen: PRAME
- Antigen Species: Human
- Peptide: SLLQHLIGL
- Conjugate: APC
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Rabbit Anti-PRAME Recombinant Antibody (clone R08-7B6) (VS3-FY1847)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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Human Anti-PRAME Recombinant Antibody (HPAB-1759LY) (HPAB-1759LY)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1701LY-F(E)) (HPAB-1701LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1702LY-F(E)) (HPAB-1702LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1703LY-F(E)) (HPAB-1703LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1704LY-F(E)) (HPAB-1704LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1705LY-F(E)) (HPAB-1705LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1754LY-F(E)) (HPAB-1754LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1755LY-F(E)) (HPAB-1755LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1756LY-F(E)) (HPAB-1756LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1757LY-F(E)) (HPAB-1757LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1758LY-F(E)) (HPAB-1758LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1759LY-F(E)) (HPAB-1759LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1748LY-F(E)) (HPAB-1748LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1749LY-F(E)) (HPAB-1749LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1750LY-F(E)) (HPAB-1750LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1751LY-F(E)) (HPAB-1751LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1752LY-F(E)) (HPAB-1752LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1753LY-F(E)) (HPAB-1753LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1742LY-F(E)) (HPAB-1742LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1743LY-F(E)) (HPAB-1743LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1744LY-F(E)) (HPAB-1744LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1745LY-F(E)) (HPAB-1745LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1746LY-F(E)) (HPAB-1746LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1747LY-F(E)) (HPAB-1747LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1736LY-F(E)) (HPAB-1736LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1737LY-F(E)) (HPAB-1737LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1738LY-F(E)) (HPAB-1738LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1739LY-F(E)) (HPAB-1739LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1740LY-F(E)) (HPAB-1740LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1741LY-F(E)) (HPAB-1741LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1730LY-F(E)) (HPAB-1730LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1731LY-F(E)) (HPAB-1731LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1732LY-F(E)) (HPAB-1732LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1733LY-F(E)) (HPAB-1733LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1734LY-F(E)) (HPAB-1734LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1735LY-F(E)) (HPAB-1735LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1724LY-F(E)) (HPAB-1724LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1725LY-F(E)) (HPAB-1725LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1726LY-F(E)) (HPAB-1726LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1727LY-F(E)) (HPAB-1727LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1728LY-F(E)) (HPAB-1728LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1729LY-F(E)) (HPAB-1729LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1718LY-F(E)) (HPAB-1718LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1719LY-F(E)) (HPAB-1719LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1720LY-F(E)) (HPAB-1720LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1721LY-F(E)) (HPAB-1721LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1722LY-F(E)) (HPAB-1722LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
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Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1723LY-F(E)) (HPAB-1723LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1712LY-F(E)) (HPAB-1712LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1713LY-F(E)) (HPAB-1713LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1714LY-F(E)) (HPAB-1714LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1715LY-F(E)) (HPAB-1715LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1716LY-F(E)) (HPAB-1716LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1717LY-F(E)) (HPAB-1717LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1706LY-F(E)) (HPAB-1706LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1707LY-F(E)) (HPAB-1707LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1708LY-F(E)) (HPAB-1708LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1709LY-F(E)) (HPAB-1709LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1710LY-F(E)) (HPAB-1710LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Human Anti-PRAME Recombinant Antibody; Fab Fragment (HPAB-1711LY-F(E)) (HPAB-1711LY-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, RIA
Compare

Anti-PRAME Immunohistochemistry Kit (VS-0525-XY5648)
- Species Reactivity: Human
- Target: PRAME
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis.

Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Spermatogonia)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (K-562)

Interaction

Component of a CRL2 E3 ubiquitin-protein ligase complex, also named ECS (Elongin BC-CUL2/5-SOCS-box protein) complex, composed of CUL2, Elongin BC (ELOB and ELOC), RBX1 and substrate-specific adapter PRAME (PubMed:21822215, 23460923, 26138980). Interacts with RARA (via the ligand-binding domain); the interaction is direct and ligand (retinoic acid)-dependent (PubMed:16179254). Interacts with EZH2; required to repress RAR signaling (PubMed:16179254).

Molecular function

Repressor

More Types Infomation