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RHO
Anti-RHO Recombinant Antibody Products
- Recombinant Anti-human RHO Antibody (MOB-849)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IP, FuncS
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- Mouse Anti-RHO Recombinant Antibody (clone Rho 1D4) (FAMAB-1247CQ)
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- Species Reactivity: Bovine, Human, Zebrafish, Amphibians, Mouse, Rat
- Type: Mouse IgG1
- Application: IB, IF, ELISA
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- Mouse Anti-RHO Recombinant Antibody (clone K42-IL) (FAMAB-1421CQ)
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- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA
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- Mouse Anti-RHO Antibody (clone Rho 1D4), mRNA (FAMAB-1247CQ-mRNA)
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- Species Reactivity: Bovine, Human, Zebrafish, Amphibians, Mouse, Rat
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- Mouse Anti-RHO Antibody (clone K42-IL), mRNA (FAMAB-1421CQ-mRNA)
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- Species Reactivity: Bovine
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- Recombinant Human Anti-human RHO Antibody Fab Fragment (MHH-849-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IF, FuncS
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- Recombinant Human Anti-human RHO Antibody scFv Fragment (MHH-849-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: Neut, IF, FuncS
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- Recombinant Anti-human RHO Antibody Fab Fragment (MOB-849-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, IF, FuncS
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- Recombinant Anti-human RHO Antibody scFv Fragment (MOB-849-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: RIA, ELISA, FuncS
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. Defects in this gene are a cause of congenital stationary night blindness.
Protein class
Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Rod photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Homodimer (By similarity). May form a complex composed of RHO, GRK1 and RCVRN in a Ca(2+)-dependent manner; RCVRN prevents the interaction between GRK1 and RHO (By similarity). Interacts with GRK1 (PubMed:28524165). Interacts (phosphorylated form) with SAG (PubMed:28524165, 26200343, 28753425). Interacts with GNAT1 (PubMed:26200343). Interacts with GNAT3. SAG and G-proteins compete for a common binding site (PubMed:26200343). Interacts with PRCD; the interaction promotes PRCD stability (By similarity).
Molecular function
G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer
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Related Signaling Pathways
cAMP Signaling Pathway