Recombinant Anti-RHO Vesicular Antibody, EV Displayed (VS-0425-YC699) (CAT#: VS-0425-YC699)

The Recombinant Anti-RHO Vesicular Antibody, EV Displayed (VS-0425-YC699) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to RHO-expressed cells or tissues. RHO, found in rod cells, is vital for low-light vision through its binding and activation with 11-cis retinal. Mutations cause night blindness.

Specific Inquiry
  • Datasheet
  • MSDS
  • COA

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • RHO
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Bovine
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Rhodopsin
  • Biological Process
  • Sensory transduction, Vision
  • Molecular Function
  • G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer
  • Introduction
  • The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. Defects in this gene are a cause of congenital stationary night blindness.

Related Resources

  • Related Signaling Pathways

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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