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UBE2M
Anti-UBE2M Recombinant Antibody Products
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- Species Reactivity: Human
- Application: WB
- AbPlus™ Anti-UBE2M Magnetic Beads (VS-0724-YC803) (VS-0724-YC803)
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- Target: UBE2M
- Target Species: Human
- Application: IP, Protein Purification
- AbPlus™ Anti-UBE2M Magnetic Beads (VS-0724-YC804) (VS-0724-YC804)
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- Target: UBE2M
- Target Species: Human, Mouse
- Application: IP, Protein Purification
- Mouse Anti-NHP UBE2M Recombinant Antibody (clone OTI2D9) (VS-1024-XY528)
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- Species Reactivity: Dog, Human, Mouse, Non-human primate
- Type: Mouse IgG1
- Application: WB, ICC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, ICC, IP, FC
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For Research Use Only. Not For Clinical Use.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HEK93)
Interaction
Interacts with UBA3 and RBX1. Interacts (N-terminally acetylated form) with (via DCUN1 domain) DCUN1D1, DCUN1D2, DCUN1D3, DCUN1D4 and DCUN1D5 (PubMed:23201271, PubMed:28581483).
Molecular function
Transferase
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