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B2M
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- PE-H2-IEd/Human B2M (IQRTPKIQVYSRHPAE) MHC Tetramer (MHC-LC2388)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: IQRTPKIQVYSRHPAE
- Conjugate: PE
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- PE-H2-IAd/Human B2M (IQRTPKIQVYSRHPAE) MHC Tetramer (MHC-LC2387)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: IQRTPKIQVYSRHPAE
- Conjugate: PE
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- PE-H2-IAd/Human B2M (HPSDIEVDLLKDGERI) MHC Tetramer (MHC-LC2386)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: HPSDIEVDLLKDGERI
- Conjugate: PE
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- PE-H2-IEd/Human B2M (IQVYSRHPAENGKSNF) MHC Tetramer (MHC-LC2393)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: IQVYSRHPAENGKSNF
- Conjugate: PE
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- PE-H2-IAd/Human B2M (IQVYSRHPAENGKSNF) MHC Tetramer (MHC-LC2392)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: IQVYSRHPAENGKSNF
- Conjugate: PE
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- PE-H2-IEd/Human B2M (SFSNDWSFYLLYYTEF) MHC Tetramer (MHC-LC2402)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: SFSNDWSFYLLYYTEF
- Conjugate: PE
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- PE-H2-IEd/Human B2M (KSNFLNCYVSGFHPSD) MHC Tetramer (MHC-LC2398)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: KSNFLNCYVSGFHPSD
- Conjugate: PE
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- PE-H2-IAd/Human B2M (KSNFLNCYVSGFHPSD) MHC Tetramer (MHC-LC2397)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: KSNFLNCYVSGFHPSD
- Conjugate: PE
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: TPKIQVYSRHPAENGKS
- Conjugate: PE
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- PE-H2-IEd/Human B2M (VTLSQPKIVKWDRDM) MHC Tetramer (MHC-LC2407)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: VTLSQPKIVKWDRDM
- Conjugate: PE
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- PE-H2-IEd/Human B2M (VDLLKDGERIEKVEHS) MHC Tetramer (MHC-LC2406)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: VDLLKDGERIEKVEHS
- Conjugate: PE
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- PE-H2-IAd/Human B2M (TEKDEYACRVNHVTLS) MHC Tetramer (MHC-LC2405)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: TEKDEYACRVNHVTLS
- Conjugate: PE
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- PE-H2-IEd/Human B2M (SFYLLYYTEFTPTEKD) MHC Tetramer (MHC-LC2404)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: SFYLLYYTEFTPTEKD
- Conjugate: PE
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- PE-H2-IEd/Human B2M (GERIEKVEHSDLSFSY) MHC Tetramer (MHC-LC2384)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: GERIEKVEHSDLSFSY
- Conjugate: PE
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- PE-H2-IAd/Human B2M (CYVSGFHPSDIEVDLL) MHC Tetramer (MHC-LC2383)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: CYVSGFHPSDIEVDLL
- Conjugate: PE
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- PE-H2-IEd/Human B2M (ACRVNHVTLSQPKIVK) MHC Tetramer (MHC-LC2380)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: ACRVNHVTLSQPKIVK
- Conjugate: PE
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- PE-H2-IAd/Human B2M (ACRVNHVTLSQPKIVK) MHC Tetramer (MHC-LC2379)
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- Class: Class II
- Antigen: B2M
- Antigen Species: Human
- Peptide: ACRVNHVTLSQPKIVK
- Conjugate: PE
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For Research Use Only. Not For Clinical Use.
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (monocytes, NK-cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Heterodimer of an alpha chain and a beta chain. Beta-2-microglobulin is the beta-chain of major histocompatibility complex class I molecules. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M alone (not in complex with HLA-I) interacts with M.tuberculosis EsxA (ESAT-6) and an EsxA-EsxB (CFP-10) complex; the tripartite complex can be detected in the host endoplasmic reticulum (PubMed:25356553). The B2M-EsxA complex can be detected in patients with pleural tuberculosis and is stable from pH 4.0 to 8.0 and in the presence of 2M NaCl (PubMed:25356553). Forms a heterotrimer with HLA-E and a self- or a foreign peptide (PubMed:9427624). Forms a heterotrimer with HLA-G and a self-peptide (PubMed:17056715). Forms a heterotrimer with HLA-F and a self-peptide (PubMed:10605026). Forms a heterotrimer with MR1 and a metabolite antigen.
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