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    PE-H2-IEd/Human B2M (GERIEKVEHSDLSFSY) MHC Tetramer (CAT#: MHC-LC2384)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human B2M of peptide GERIEKVEHSDLSFSY and H2-IEd molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
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    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, cytosol & the Golgi apparatus.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6361/if_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & the Golgi apparatus.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/if_selected.jpg
    Normal Tissue
    Figure 3 Spleen
    Figure 3 Spleen
    (High expression in spleen)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6361/18752_B_7_4_val_selected.jpg
    Figure 4 Bone marrow
    Figure 4 Bone marrow
    (Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_B_6_4.jpg
    Figure 5 Lymph node
    Figure 5 Lymph node
    (Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_A_8_8.jpg
    Figure 6 Cerebral cortex
    Figure 6 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_B_8_5.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_A_8_5.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166710-B2M

    Specifications

    • Allele
    • H2-IEd
    • Class
    • Class II
    • MHC Species
    • Mouse
    • Antigen
    • B2M
    • Antigen Species
    • Human
    • Peptide
    • GERIEKVEHSDLSFSY
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • β2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the β2 microglobulin protein[5] is encoded by the B2M gene.
    • Alternative Names
    • B2M; Beta-2-microglobulin

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    CAT Product Name Application Type
    MOB-1431z-F(E) Recombinant Anti-Human B2M Antibody Fab Fragment Neut, WB, FuncS Fab
    HPAB-0130-FY-F(E) Human Anti-B2M Recombinant Antibody (clone B2M-1D8); Fab Fragment ELISA Humanized Fab
    HPAB-0131-FY-F(E) Human Anti-B2M Recombinant Antibody (clone B2M-2F6); Fab Fragment ELISA Humanized Fab
    HPAB-0350-FY-F(E) Mouse Anti-B2M Recombinant Antibody (clone FY-007); Fab Fragment ELISA Mouse Fab

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