10-FnIII scaffold protein anti-Human Albumin
CAT#: SFN-L021
The tenth fibronectin type III domain (10Fn3) that bound albumin was isolated from the library using phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=5 μΜ) for albumin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line Hep G2
Immunofluorescent staining of human cell line Hep G2 shows localization to endoplasmic reticulum & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/763_G10_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human fallopian tube
Immunohistochemical staining of human fallopian tube shows distinct positivity in plasma.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6262/17728_A_9_7_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/128566_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/128566_A_7_3.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining:Medium
Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/128566_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/128566_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163631-ALB
❮
❯
Specifications
- Scaffold Name
- 10-FnIII
- Origin
- Fibronectin
- Core Structure
- β-sandwich of 7 β-strands
- Variable Regions
- 2–3 Loops
- Target
- Albumin
- Species Reactivity
- Human
- Expression Host
- BL21 (DE3) cells
- Affinity Constant
- 5 μΜ
- Applications
- ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for SFN-L021. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ALB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-81-sdAb | Recombinant Anti-human ALB VHH Single Domain Antibody | IHC, ICC, IP, ChiP, Neut | Llama VHH |
| PNBL-002 | Recombinant Anti-Human, mouse, and rat ALB IgNAR Antibody (PNBL-002) | ELISA | Shark IgNAR |
| PABX-001-VHH | Recombinant Anti-Human Albumins VHH Single Domain Antibody (PABX-001-VHH) | ELISA | Shark VHH |
| NBD-0046-YJ-VHH | Camelid Anti-ALB Recombinant Single Domain Antibody (NBD-0046-YJ-VHH) | ELISA, FC | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0527CL | Human Anti-ALB Recombinant Antibody (TAB-0527CL) | ELISA | Humanized Antibody |
| TAB-0528CL | Human Anti-ALB Recombinant Antibody (TAB-0528CL) | ELISA | Humanized Antibody |
| TAB-0529CL | Human Anti-ALB Recombinant Antibody (TAB-0529CL) | ELISA | Humanized Antibody |
| TAB-0511CL-S(P) | Human Anti-ALB Recombinant Antibody scFv Fragment (TAB-0511CL-S(P)) | ELISA | Humanized Antibody |
| TAB-0512CL-S(P) | Human Anti-ALB Recombinant Antibody scFv Fragment (TAB-0512CL-S(P)) | ELISA | Humanized Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-431CT | Anti-Human Serum Albumin Recombinant Antibody (DOM7r31) | WB, ELISA | Human antibody |
| TAB-432CT | Anti-Human Serum Albumin Recombinant Antibody (DOM7r36) | WB, ELISA | Human antibody |
| TAB-433CT | Anti-Human Serum Albumin Recombinant Antibody (DOM7r92) | WB, ELISA | Human antibody |
| TAB-433CT-S(P) | Anti-Human Serum Albumin Recombinant Antibody scFv Fragment (DOM7r92) | WB, ELISA | Human antibody |
| TAB-431CT-F(E) | Anti-Human Serum Albumin Recombinant Antibody Fab Fragment (DOM7r31) | WB, ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0672MZ | Chicken Anti-Albumin Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0132 | Hi-Affi™ Rabbit Anti-ALB Recombinant Antibody (clone DS132AB) | WB, IHC, FC | Rabbit IgG |
| MOR-0133 | Hi-Affi™ Rabbit Anti-ALB Recombinant Antibody (clone DS133AB) | ELISA, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0047-CN | Rabbit Anti-ALB Recombinant Antibody (clone JF32-10) | WB, IHC | Rabbit IgG |
| MRO-2182-CN | Rabbit Anti-ALB Polyclonal Antibody (MRO-2182-CN) | WB | Rabbit IgG |
| VS7-HM73 | Mouse Anti-ALB Recombinant Antibody (clone CBL028HM) | WB, ELISA | Mouse IgG |
| VS7-HM74 | Mouse Anti-ALB Recombinant Antibody (clone CBL029HM) | WB | Mouse IgG |
| VS7-0425-WR106 | Mouse Anti-ALB Monoclonal Antibody (clone 8F6F9) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0663-WJ-F(E) | Human Anti-ALB Recombinant Antibody; Fab Fragment (HPAB-0663-WJ-F(E)) | ELISA | Humanized Fab |
| PFBS-0046 | Rabbit Anti-ALB Recombinant Antibody; Fab Fragment (PFBS-0046) | ELISA, FuncS | Rabbit Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0663-WJ-S(P) | Human Anti-ALB Recombinant Antibody; scFv Fragment (HPAB-0663-WJ-S(P)) | ELISA | Human scFv |
| PSBS-0046 | Rabbit Anti-ALB Recombinant Antibody; scFv Fragment (PSBS-0046) | ELISA, FuncS | Rabbit scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC827 | AbPlus™ Anti-ALB Magnetic Beads (VS-0724-YC827) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY116 | Human Anti-ALB scFv-Fc Chimera (VS-0125-FY116) | ELISA, FC, FuncS | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY86 | Anti-ALB Immunohistochemistry Kit | IHC | |
| VS-0525-XY288 | Anti-Mouse ALB Immunohistochemistry Kit | IHC | |
| VS-0525-XY287 | Anti-Human ALB Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IHC-Fr, IP, ELISA, Block
Application: Neut, ELISA, WB, SPR, IF, EM
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
