A*0201/HBV HBsAg (GLSPTVWLSV) MHC Tetramer
CAT#: MHC-LC732
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HBV-derived peptide of GLSPTVWLSV sequence covering 185-194 and A*0201 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- A*0201
- Class
- Class I
- MHC Species
- Human
- Antigen
- HBV HBsAg
- Antigen Species
- HBV
- Peptide
- GLSPTVWLSV
- Range
- 185-194
- Application
- FCM
Target
- Antigen Introduction
- Hepatitis B virus, abbreviated HBV, is of the double stranded DNA type, a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B.
- Alternative Names
- HBV surface antigen; Hepatitis B virus surface antigen; HBsAg
- Gene ID
- 944569
- UniProt ID
- Q2F515
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Effective HBV Antigen Detection
This tetramer was very useful for detecting human CD8 T cells specific to the HBV HBsAg peptide GLSPTVWLSV. The A*0201 restriction was accurate, and we obtained clear results in our flow cytometry experiments.
Consistent for Viral Immunology
We relied on this product to analyze T cell responses to Hepatitis B virus. The tetramer formed with the 185-194 peptide sequence provided consistent staining, allowing us to quantify specific T cells reliably.
Q&As
-
Which Hepatitis B peptide is presented by this tetramer?
A: This tetramer presents the HBsAg (Hepatitis B surface antigen) peptide with the sequence GLSPTVWLSV. This corresponds to residues 185-194 and is presented by the human HLA-A*0201 molecule.
-
Is this product useful for analyzing immune responses to HBV?
A: Yes, this tetramer is a valuable tool for identifying and quantifying human CD8 T cells specific for the HBV surface antigen, aiding in the analysis of immune responses to the virus.
View the frequently asked questions answered by Creative Biolabs Support.
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Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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