APC-A*02:01/Human AFP (PLFQVPEPV) MHC Tetramer (CAT#: MHC-LC1653)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of AFP-derived peptide of PLFQVPEPV covering 137-145 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10607/1816_H10_5_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10607/1816_H10_5_selected.jpg
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong positivity in plasma.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10607/25809_A_2_7_selected.jpg
(Immunohistochemical staining of human placenta shows strong positivity in plasma.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10607/25809_A_2_7_selected.jpg
Figure 3 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081051-AFP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081051-AFP
Figure 3 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081051-AFP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081051-AFP
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- AFP
- Antigen Species
- Human
- Peptide
- PLFQVPEPV
- Range
- 137-145
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
- Alternative Names
- AFP; alpha fetoprotein; AFPD; FETA; HPAFP
- Gene ID
- 174
- UniProt ID
- P02771
Downloads
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See other products for "AFP"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1278z | Mouse Anti-AFP Recombinant Antibody (clone 26D4) | WB, IP, ELISA | Mouse IgG1 |
| HPAB-0296-FY | Mouse Anti-AFP Recombinant Antibody (clone Ab1) | IA, ELISA, IF, IH | Mouse IgG |
| HPAB-0297-FY | Mouse Anti-AFP Recombinant Antibody (clone Ab2) | IA, ELISA, IF, IH | Mouse IgG |
| HPAB-0298-FY | Mouse Anti-AFP Recombinant Antibody (clone Ab3) | ELISA, IF, IHC | Mouse IgG |
| ZG-0265F | Mouse Anti-AFP Recombinant Antibody (ZG-0265F) | WB, ELISA | Mouse IgG |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-011 | Recombinant Anti-Human AFP VHH Single Domain Antibody | CA, IP, IF, FuncS | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-713 | Humanized Anti-AFP Recombinant Antibody (clone Tacatuzumab) | IF, IP, Neut, FuncS, ELISA, FC, WB | Humanized (from mouse) IgG1, κ |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G071G | Anti-AFP immunotoxin 80G (F (ab')2)-Gel | Cytotoxicity assay, Function study | |
| AGTO-G072G | Anti-AFP immunotoxin 80G (IgG)-Gel | Cytotoxicity assay, Function study |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0029MZ | Chicken Anti-AFP Polyclonal IgY | WB | Chicken antibody |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0099 | Hi-Affi™ Rabbit Anti-AFP Recombinant Antibody (clone DS99AB) | IHC-P, IP, WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0017-YC-S(P) | Mouse Anti-AFP Recombinant Antibody (clone AF5); scFv Fragment | WB | Mouse scFv |
| HPAB-0296-FY-S(P) | Mouse Anti-AFP Recombinant Antibody (clone Ab1); scFv Fragment | ELISA, IF, IHC | Mouse scFv |
| HPAB-0297-FY-S(P) | Mouse Anti-AFP Recombinant Antibody (clone Ab2); scFv Fragment | ELISA, IF, IHC | Mouse scFv |
| HPAB-0298-FY-S(P) | Mouse Anti-AFP Recombinant Antibody (clone Ab3); scFv Fragment | ELISA, IF, IHC | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0017-YC-F(E) | Mouse Anti-AFP Recombinant Antibody (clone AF5); Fab Fragment | WB | Mouse Fab |
| HPAB-0296-FY-F(E) | Mouse Anti-AFP Recombinant Antibody (clone Ab1); Fab Fragment | ELISA, IF, IHC | Mouse Fab |
| HPAB-0297-FY-F(E) | Mouse Anti-AFP Recombinant Antibody (clone Ab2); Fab Fragment | ELISA, IF, IHC | Mouse Fab |
| HPAB-0298-FY-F(E) | Mouse Anti-AFP Recombinant Antibody (clone Ab3); Fab Fragment | ELISA, IF, IHC | Mouse Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-713 | Afuco™ Anti-AFP ADCC Recombinant Antibody (Tacatuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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