Mouse Anti-ACHE Recombinant Antibody (clone Fab408) (CAT#: PABL-374)
Recombinant Mouse Antibody (Fab408) is capable of binding to AChE.
Specific Inquiry
Figure 1 SDS-PAGE analysis of AChE antibody Fab408.
Electrophoresis patterns obtained by SDS-PAGE in non-reducing conditions (12.5% PhastGel, left) and native-PAGE (7.5% PhastGel, center) with migration from the cathode (top) toward the anode (bottom), and by isoelectric focusing (pI 3-9 PhastGel, right). The three Fabs are more homogenous in mass than in charge, a feature that likely result from variations in the C-terminus generated by papaine cleavage of the CH chain; yet, all isoforms bind EeAChE equally, as verified by a native-PAGE mobility shift assay (not shown). The neutral average pI of Fab408 and cationic average pIs of Fab403 and Fab410 are evident.
Bourne, Y., Renault, L., Essono, S., Mondielli, G., Lamourette, P., Boquet, D., ... & Marchot, P. (2013). Molecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor region. PLoS One, 8(10), e77226.
Specifications
- Immunogen
- Human acetylcholinesterase (Cartwright blood group)
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Specificity
- Human ACHE
- Species Reactivity
- Human
- Clone
- Fab408
- Applications
- WB, ELISA, FuncS
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-31 | Recombinant Anti-human ACHE Antibody | ELISA, WB, FuncS | IgG |
| MHH-31 | Recombinant Human Anti-human ACHE Antibody | FC, ELISA, FuncS | IgG |
| PABL-375 | Recombinant Mouse Anti-BfAChE Antibody (Fab410) | WB, ELISA, FuncS | IgG |
| PABZ-040 | Recombinant Mouse Anti-Electric eel AChE Antibody (mAb408) | BL | IgG |
| MOB-0410MZ | Mouse Anti-ACHE Recombinant Antibody (clone 23C5) | ELISA, WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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