Mouse Anti-ACKR3 Recombinant Antibody; Fab Fragment (TAB-172MZ-F(E))
CAT#: TAB-172MZ-F(E)
This product is a recombinant mouse antibody Fab fragment that recognizes CXCR7. The antibody was purified by affinity chromatography.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32003/1048_F7_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows cytoplasmic positivity in trophoblasts.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49718/116961_A_2_7_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32003/1047_F7_1_blue_red_green.jpg
Normal Tissue
Figure 4 Pancreas
Exocrine glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49718/116961_A_1_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49718/116961_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49718/116961_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HeLa, MCF7, RT4, SiHa, U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144476-ACKR3
❮
❯
Specifications
- Immunogen
- cDNA expressing CXCR7
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human CXCR7
- Species Reactivity
- Human
- Applications
- Flow Cytometry
- Related Disease
- Cancers, such as gliomas, mesotheliomas, melanomas
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ACKR3; atypical chemokine receptor 3; RDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159; G protein-coupled receptor; chemokine orphan receptor 1; G-protein coupled receptor 159; C-X-C chemokine receptor type 7; chemokine (C-X-C motif) receptor 7; G-protein coupled receptor RDC1 homolog
- Gene ID
- 57007
- UniProt ID
- P25106
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
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