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Afuco™ Anti-Human AREG ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-052CL)

Anti-AREG ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Anti-AR antibodies are humanized monoclonal antibodies used for inhibiting cancer cell growth, treating cancer or psoriasis.


See more Engineered Antibody products for AREG
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Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23519/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human placenta
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong membranous positivity in cytotrophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8720/156789_A_1_7_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8720/156789_B_7_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8720/156789_A_7_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8720/156789_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Preleptotene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8720/156789_A_6_6.jpg
Figure 7 Placenta
Figure 7 Placenta
(Trophoblastic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8720/156789_A_1_7.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (CACO-2, HBEC3-KT, hTCEpi, hTERT-HME1, MCF7)
Figure 8 RNA cell line category: Cell line enhanced (CACO-2, HBEC3-KT, hTCEpi, hTERT-HME1, MCF7)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109321-AREG

Specifications

  • Host Species
  • Humanized
  • Derivation
  • Humanized
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Cancer; Psoriasis

Product Property

  • Purity
  • >95% as judged by SDS-polyacrylamide gel electrophoresis
  • Storage
  • Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.

Target

  • Alternative Names
  • AREG; amphiregulin; AR; SDGF; AREGB; CRDG

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "AREG"

Recombinant Antibody

CAT Product Name Application Type
MOB-3885z Mouse Anti-AREG Recombinant Antibody (clone 43B6) WB, IP, IF, IHC, ELISA Mouse IgG1, κ
MOB-0613MZ Mouse Anti-AREG Recombinant Antibody (clone NN0090-9L27) WB Mouse IgG1

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0037MZ Chicken Anti-Amphiregulin Polyclonal IgY WB Chicken antibody
BRD-0939MZ Chicken Anti-Amphiregulin Polyclonal IgY WB Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-025CQ Mouse Anti-AREG Recombinant Antibody (clone CBL747) WB, ELISA(Cap), Neut Mouse IgG1

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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