Anti-BNP antibody is a Mouse antibody of IgG1 class that binds to an BNP. This antibody binds an epitope spanning residues 5-13 of the mature bioactive peptide.
Figure 1 Equilibrium binding titration of Alexa488-BNP 5-13 with mAb 106.3 at various temperatures.
The dissociation constants are: 0.05 nM, 0.07 nM, 0.2 nM, 0.6 nM, 1.2 nM, 3.4 nM, 7.2 nM.
Longenecker, K. L., Ruan, Q., Fry, E. H., Saldana, S. C., Brophy, S. E., Richardson, P. L., & Tetin, S. Y. (2009). Crystal structure and thermodynamic analysis of diagnostic mAb 106.3 complexed with BNP 5‐13 (C10A). Proteins: Structure, Function, and Bioinformatics, 76(3), 536-547.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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