Mouse Anti-NPPB scFv-Fc Chimera (VS-0325-FY189) (CAT#: VS-0325-FY189)

• Immunogen
• The NT-proBNP epitope prediction design, 76 amino acid molecule, the synthesis of the two linear epitope conjugated KLH immunization, the antibody Abl immune found 5-27 amino acid linear epitope obtained, Ab5 amino acids 61-76 of an antibody immune linear epitope obtained.

• Host Species
• Mouse

• Type
• Mouse IgG1, scFv-Fc

• Specificity
• Human NPPB

• Species Reactivity
• Human

• Applications
• ELISA

• Purity
• >95% as determined by SDS-PAGE

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Alternative Names
• Natriuretic Peptide B; Natriuretic Peptide Precursor B; Gamma-Brain Natriuretic Peptide; Brain Type Natriuretic Peptide; Natriuretic Peptides B; Natriuretic Protein; BNP; ProBNP

• Gene ID
• 4879

• UniProt ID
• P16860

• Long Name
• Natriuretic Peptide B

• Sequence Similarities
• Belongs to the natriuretic peptide family.

• Cellular Localization
• Secreted

• Post Translation Modifications
• The precursor molecule is proteolytically cleaved by the endoproteases FURIN or CORIN at Arg-102 to produce brain natriuretic peptide 32 and NT-proBNP.
  Glycosylation at Thr62, Ser63, Ser70, Thr74, Ser79, Thr84, and Thr97
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyGen 8 sites, 1 O-linked glycan (4 sites)

• Protein Refseq
• NP_002512.1

• Function
• Human NPPB (Natriuretic peptide B) is a cardiac hormone secreted by the ventricles in response to increased ventricular volume and pressure. It plays a crucial role in regulating fluid balance and blood pressure, and is used as a biomarker for heart failure.

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

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