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NPPB

Anti-NPPB Products
- Recombinant Mouse Anti-BNP Antibody (106.3) (PABX-017)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: FuncS
- Human Anti-NPPB Recombinant Antibody (clone 3C1) (HPAB-0476-YJ)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, DB, Neut
- Mouse Anti-NPPB Recombinant Antibody (clone 8C7E11) (HPAB-0477-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, LF
- Human Anti-NPPB Antibody, mRNA (TAB-692CL-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC, ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Mouse Anti-Human NPPB Antibody (MOB-0403ZL)
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- Species Reactivity: Human
- Application: ELISA, Immunoassay, WB
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IA, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Mouse Anti-NPPB Recombinant Antibody (clone 3A6F7C7) (VS3-XY1178)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IHC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Mouse Anti-NPPB Recombinant Antibody (clone 8C7E11); scFv Fragment (HPAB-0477-YJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, LF
- Human Anti-NPPB Recombinant Antibody (clone 3C1); Fab Fragment (HPAB-0476-YJ-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, DB, Neut
- Mouse Anti-NPPB Recombinant Antibody (clone 8C7E11); Fab Fragment (HPAB-0477-YJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, LF
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- Species Reactivity: Human
- Type: Antibody
- Recombinant Mouse Anti-BNP Antibody scFv Fragment (106.3) (PABX-017-S (P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, IF, FuncS
- Recombinant Mouse Anti-BNP Antibody Fab Fragment (106.3) (PABX-017-F (E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, IF, FuncS
- Human Anti-NPPB Recombinant Antibody (clone 3C1); scFv Fragment (HPAB-0476-YJ-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, DB, Neut
- Anti-Mouse NPPB Immunohistochemistry Kit (VS-0525-XY4926)
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- Species Reactivity: Human, Mouse, Rat
- Target: NPPB
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
- Mouse Anti-NPPB scFv-Fc Chimera (VS-0325-FY189) (VS-0325-FY189)
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- Species Reactivity: Human
- Type: Mouse IgG1, scFv-Fc
- Application: ELISA
- Mouse Anti-NPPB Monoclonal Antibody (VS7-0425-WR496) (VS7-0425-WR496)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC-P, IF, ELISA
- Anti-NPPB Immunohistochemistry Kit (VS-0525-XY4925)
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- Species Reactivity: Human
- Target: NPPB
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
Protein class
Candidate cardiovascular disease genes, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Cardiomyocytes, Ductal cells, Pancreatic endocrine cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BEWO, CACO-2, SuSa)
Molecular function
Hormone, Vasoactive, Vasodilator
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