Afuco™ Anti-Human CCR6 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-098CL
Anti-CCR6 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an antibody which can bind to human CCR6 with high affinity and has a neutralizing activity.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_B_8_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_9_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_8_5.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6820/17235_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (Hep G2, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112486-CCR6
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Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- CCR6; chemokine (C-C motif) receptor 6; BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6; C-C chemokine receptor type 6; LARC receptor; chemokine receptor-like 3; chemokine (C-C) receptor 6; G protein-coupled receptor 29; G-protein coupled receptor 29; seven-transmembrane receptor, lymphocyte, 22
- Gene ID
- 1235
- UniProt ID
- P51684
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| TAB-1543CL-S(P) | Anti-Human CCR6 Recombinant Antibody scFv Fragment (MSM-R605) | FC | Fully human antibody |
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| TAB-1544CL-F(E) | Anti-Human CCR6 Recombinant Antibody Fab Fragment (MSM-R606) | FC | Fully human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0097MZ | Chicken Anti-CCR6 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0082-CN | Mouse Anti-CCR6 Recombinant Antibody (HPAB-0082-CN) | Neut, ELISA, FC | Mouse IgG |
| HPAB-0084-CN | Human Anti-CCR6 Recombinant Antibody (HPAB-0084-CN) | Neut, ELISA, FC | Humanized IgG |
| HPAB-0085-CN | Human Anti-CCR6 Recombinant Antibody (HPAB-0085-CN) | Neut, ELISA, FC | Humanized IgG1 |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0082-CN-F(E) | Mouse Anti-CCR6 Recombinant Antibody; Fab Fragment (HPAB-0082-CN-F(E)) | Neut, ELISA, FC | Mouse Fab |
| HPAB-0084-CN-F(E) | Human Anti-CCR6 Recombinant Antibody; Fab Fragment (HPAB-0084-CN-F(E)) | Neut, ELISA, FC | Humanized Fab |
| HPAB-0083-CN-F(E) | Human Anti-CCR6 Recombinant Antibody; Fab Fragment (HPAB-0083-CN-F(E)) | Neut, ELISA, FC | Chimeric (mouse/human) Fab |
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| HPAB-AP026-YC-F(E) | Human Anti-CCR6 Recombinant Antibody (clone R619); Fab Fragment | FC, IF | Human Fab |
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|---|---|---|---|
| VS-0225-XY12 | CytoStream™ Rat Anti-CCR6 Recombinant Antibody (clone 140706) | FC | Rat IgG2a |
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| VS-0425-YC641 | Recombinant Anti-CCR6 Vesicular Antibody, EV Displayed (VS-0425-YC641) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
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| VS-0525-XY1103 | Anti-CCR6 Immunohistochemistry Kit | IHC |
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