Anti-CD23 Recombinant Antibody Lumiliximab(Lumiliximab)
CAT#: TAB-760
Recombinant chimeric (primate/human) antibody expressed in CHO. Lumiliximab is a monoclonal antibody that targets CD23. It acts as an immunomodulator. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
Gene Expression
Normal Tissue
Figure 1 Bone marrow
Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104921-FCER2
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- primate
- Derivation
- Chimeric (primate/human)
- Type
- IgG1 - kappa
- Species Reactivity
- Human
- Applications
- Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
- CAS
- 357613-86-6
- Generic Name
- lumiliximab
- UNII
- 8Z13S29R5A
- MW
- 47.75 kDa
- Related Disease
- Allergic asthma
Product Property
- Purity
- >95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- At -20°C for one year.
Target
- Alternative Names
- lumiliximab;357613-86-6;IDEC-152;P5E8;gomiliximab;FCER2;Fc fragment of IgE, low affinity II, receptor for (CD23);CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2;low affinity immunoglobulin epsilon Fc receptor;CD23;CLEC4J;BLAST-2;CD
- Gene ID
- 2208
- UniProt ID
- P06734
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Lumiliximab"
Afuco™ Anti-CD23 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-760)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant chimeric (primate/human) antibody expressed in CHO. It is a monoclonal antibody that targets CD23. It acts as an immunomodulator. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
DrugMonitor™ Anti-Lumiliximab Antibody (VS-1224-YC693)Lumiliximab is a chimeric monoclonal antibody serving as an immunosuppressive drug, a primatized macaque/human anti-CD23 antibody for potentially treating allergic conditions. The DrugMonitor™ Anti-Lumiliximab Antibody (VS-1224-YC693) is an anti-drug antibody (ADA) against Lumiliximab. This drug-based antibody is raised in mice immunized with the Lumiliximab. The anti-Lumiliximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Lumiliximab in samples.
See other products for "CD23"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4037 | Hi-Affi™ Rabbit Anti-CD23 Recombinant Antibody (clone SI104DS) | FC | Rabbit IgG |
| MOR-4038 | Hi-Affi™ Rabbit Anti-CD23 Recombinant Antibody (clone SI105DS) | ICC, IF, FC | Rabbit IgG |
| MOR-4039 | Hi-Affi™ Rabbit Anti-CD23 Recombinant Antibody (clone SI106DS) | FC | Rabbit IgG |
| MOR-4040 | Hi-Affi™ Rabbit Anti-CD23 Recombinant Antibody (clone SI107DS) | FC | Rabbit IgG |
| MOR-4041 | Hi-Affi™ Rabbit Anti-CD23 Recombinant Antibody (clone SI108DS) | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-760 | Afuco™ Anti-CD23 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-760) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY358 | Anti-CD23 Immunohistochemistry Kit | IHC |
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