Afuco™ Anti-CD23 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-760) (CAT#: AFC-TAB-760)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant chimeric (primate/human) antibody expressed in CHO. It is a monoclonal antibody that targets CD23. It acts as an immunomodulator. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
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Normal Tissue
RNA Expression
Figure 1 Bone marrow
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
Figure 2 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104921-FCER2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104921-FCER2
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Primate
- Derivation
- Chimeric (primate/human)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- IP, IF, FuncS, FC, Neut, ELISA
- Conjugate
- Unconjugated
- Generic Name
- Lumiliximab
- Related Disease
- Allergic asthma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A), FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2;
- Gene ID
- 2208
- UniProt ID
- P06734
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "lumiliximab"
Anti-CD23 Recombinant Antibody Lumiliximab(Lumiliximab)Recombinant chimeric (primate/human) antibody expressed in CHO. Lumiliximab is a monoclonal antibody that targets CD23. It acts as an immunomodulator. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
DrugMonitor™ Anti-Lumiliximab Antibody (VS-1224-YC693)Lumiliximab is a chimeric monoclonal antibody serving as an immunosuppressive drug, a primatized macaque/human anti-CD23 antibody for potentially treating allergic conditions. The DrugMonitor™ Anti-Lumiliximab Antibody (VS-1224-YC693) is an anti-drug antibody (ADA) against Lumiliximab. This drug-based antibody is raised in mice immunized with the Lumiliximab. The anti-Lumiliximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Lumiliximab in samples.
See other products for "CD23"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-760 | Anti-CD23 Recombinant Antibody Lumiliximab(Lumiliximab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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