Afuco™ Anti-Human CD55 ADCC Recombinant Antibody (PAT-SC1), ADCC Enhanced
CAT#: AFC-126CL
Anti-CD55 ADCC Enhanced Antibody (PAT-SC1) is an ADCC enhanced antibody produced by our Afuco™ platform. PAT-SC1 has a strong potential to be used as an additive therapeutic agent in the treatment of patients with gastric cancers. A study conducted between 1997 and 2001, a single 20mg dose of PAT-SC1 administered before gastric resection surgery induced cell killing in human primary gastric tumours. This led to tumour cell regression in over half of PAT-SC1-treated patients. In the 10 year follow-up study of patients that participated in the trial, survival is significantly higher for PAT-SC1 treated patients as compared to an historical control group of patients that underwent a gastric resection but were not treated with PAT-SC1.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_B_8_5.jpg
Normal Tissue
Figure 2 Lung
Alveolar cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_1_4.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_8_3.jpg
Normal Tissue
Figure 4 Testis
Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_4_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4 °C, -20°C if preferred
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1214z | Mouse Anti-CD55 Recombinant Antibody (clone 43C4) | WB, ELISA, IHC | Mouse IgG1, λ |
| HPAB-0054-YJ | Human Anti-CD55 Recombinant Antibody (clone LU30) | FC, ELISA, IHC | Human IgG1 |
| VS2-QX14 | Mouse Anti-CD55 Recombinant Antibody (clone BRIC 110) | IHC, WB | Mouse IgG1, κ |
| VS2-QX16 | Mouse Anti-CD55 Recombinant Antibody (clone BRIC 216) | IHC, WB | Mouse IgG1, κ |
| VS2-QX17 | Mouse Anti-CD55 Recombinant Antibody (clone BRIC 230) | IB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-316LC | Human Anti-CD55 Recombinant Antibody (TAB-316LC) | ELISA, FC, Inhib | Human IgG1 |
| TAB-316LC-S(P) | Human Anti-CD55 Recombinant Antibody; scFv Fragment (TAB-316LC-S(P)) | ELISA | Human scFv |
| TAB-316LC-F(E) | Human Anti-CD55 Recombinant Antibody; Fab Fragment (TAB-316LC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0102MZ | Chicken Anti-CD55 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-393CQ | Mouse Anti-CD55 Recombinant Antibody (clone CBL021) | Neut, WB | Mouse IgG2 |
| NEUT-394CQ | Mouse Anti-CD55 Recombinant Antibody (clone MM0175-12L29) | IHC-P, WB, Neut | Mouse IgG2 |
| NEUT-395CQ | Mouse Anti-CD55 Recombinant Antibody (clone CBL739) | WB, Neut | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0570 | Hi-Affi™ Rabbit Anti-CD55 Recombinant Antibody (clone DS570AB) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0498-CN-S(P) | Mouse Anti-CD55 Recombinant Antibody; scFv Fragment (HPAB-0498-CN-S(P)) | ELISA, FC, Neut | Mouse scFv |
| HPAB-0054-YJ-S(P) | Human Anti-CD55 Recombinant Antibody (clone LU30); scFv Fragment | FC, ELISA, IHC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0498-CN-F(E) | Mouse Anti-CD55 Recombinant Antibody; Fab Fragment (HPAB-0498-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0054-YJ-F(E) | Human Anti-CD55 Recombinant Antibody (clone LU30); Fab Fragment | FC, ELISA, IHC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS2-QX15 | Mouse Anti-CD55 Recombinant Antibody (clone BRIC 128) | IHC, WB | Mouse IgM, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC463 | AbPlus™ Anti-CD55 Magnetic Beads (VS-0724-YC463) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY103 | Mouse Anti-NHP CD55 Recombinant Antibody (clone MEM-118) | IHC, FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY60 | CytoStream™ Mouse Anti-CD55 Recombinant Antibody (VS-0225-XY60) | FC | Mouse IgG2a, kappa |
| VS-0225-XY61 | CytoStream™ Armenian Hamster Anti-CD55 Recombinant Antibody (clone RIKO-5) | FC | Armenian Hamster IgG3, lambda |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY204 | Human Anti-CD55 (clone LU30) scFv-Fc Chimera | FC, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC184 | Recombinant Anti-CD55 Vesicular Antibody, EV Displayed (VS-0425-YC184) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1200 | Anti-CD55 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1201 | Anti-Human CD55 Immunohistochemistry Kit | IHC |
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