Afuco™ Anti-Human CD55 ADCC Recombinant Antibody (PAT-SC1), ADCC Enhanced (CAT#: AFC-126CL)
Anti-CD55 ADCC Enhanced Antibody (PAT-SC1) is an ADCC enhanced antibody produced by our Afuco™ platform. PAT-SC1 has a strong potential to be used as an additive therapeutic agent in the treatment of patients with gastric cancers. A study conducted between 1997 and 2001, a single 20mg dose of PAT-SC1 administered before gastric resection surgery induced cell killing in human primary gastric tumours. This led to tumour cell regression in over half of PAT-SC1-treated patients. In the 10 year follow-up study of patients that participated in the trial, survival is significantly higher for PAT-SC1 treated patients as compared to an historical control group of patients that underwent a gastric resection but were not treated with PAT-SC1.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_B_8_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_B_8_5.jpg
Figure 2 Lung
(Alveolar cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_1_4.jpg
(Alveolar cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_1_4.jpg
Figure 3 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_8_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_8_3.jpg
Figure 4 Testis
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_4_6.jpg
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_4_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4 °C, -20°C if preferred
Target
- Alternative Names
- CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CR; TC; DAF; CROM; complement decay-accelerating factor; CD55 antigen
- Gene ID
- 1604
- UniProt ID
- P08174
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1214z | Mouse Anti-CD55 Recombinant Antibody (clone 43C4) | WB, ELISA, IHC | Mouse IgG1, λ |
| MOB-0163CT | Mouse Anti-CD55 Recombinant Antibody (clone CSJD 327) | FC, IP, WB | Mouse IgG1 |
| HPAB-0498-CN | Mouse Anti-CD55 Recombinant Antibody (HPAB-0498-CN) | ELISA, FC, Neut | Mouse IgG |
| HPAB-0054-YJ | Human Anti-CD55 Recombinant Antibody (clone LU30) | FC, ELISA, IHC | Human IgG1 |
| VS3-WK1487 | Mouse Anti-CD55 Recombinant Antibody (clone COB55) | FC, IF | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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