Anti-Human CDH1 Recombinant Antibody (SC10.17) (CAT#: TAB-1410CL)
This antibody is a CD324 modulator, which can be used in the treatment of CD324 associated disorders (e.g., hyperproliferative disorders or neoplastic disorders).
Specific Inquiry
Figure 1 Comparative binding affinities of a selected murine modulator and its humanized counterpart.
Inhib
Figure 2 The ability of the disclosed modulators to inhibit CD324 homotypic binding.
Figure 3 Humanized CD324 modulators may effectively be used as targeting moieties to direct cytotoxic payloads to cells expressing CD324, wherein the decrease in normalized RLU value is indicative of cell killing through internalized toxin and where the determined EC50 (e.g., half-maximal effective concentration) values are indicative of efficient cell killing.
Specifications
- Immunogen
- Human CD324-His recombinant protein (Sino Biological, Inc.)
- Host Species
- Mouse
- Specificity
- Human
- Clone
- SC10.17
- Applications
- Inhib
- Related Disease
- CD324 associated disorders (e.g., hyperproliferative disorders or neoplastic disorders)
Applications
- Application Notes
- This antibody has been tested for use in Inhibition.
Target
- Alternative Names
- CDH1; cadherin 1, type 1, E-cadherin (epithelial); UVO; CDHE; ECAD; LCAM; Arc-1; CD324; cadherin-1; CAM 120/80; E-Cadherin; uvomorulin; cell-CAM 120/80; epithelial cadherin; cadherin 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial;
- Gene ID
- 999
- UniProt ID
- P12830
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1411CL | Anti-Human CDH1 Recombinant Antibody (hSC10.17) | Cyt, FuncS, Inhib | Humanized antibody |
| TAB-1411CL-S(P) | Anti-Human CDH1 Recombinant Antibody scFv Fragment (hSC10.17) | ELISA | Humanized antibody |
| TAB-1411CL-F(E) | Anti-Human CDH1 Recombinant Antibody Fab Fragment (hSC10.17) | ELISA | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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