Anti-Human CDH1 Recombinant Antibody scFv Fragment (hSC10.17)
CAT#: TAB-1411CL-S(P)
This is an anti-CD324 modulator, a humanized scFv antibody. humanized CD324 modulator antibody can kill CD324-expressing cells. This antibody is the scfv fragment antibody format of IgG antibody.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, the Golgi apparatus & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28364/672_E7_2_selected.jpg
Normal Tissue
Figure 2 ParaThyroid gland
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4812/158154_A_3_8_val_selected.jpg
Normal Tissue
Figure 3 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Microvilli Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_7_5.jpg
Normal Tissue
Figure 1 Urinary bladder
Urothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_5_5.jpg
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (BEWO, CACO-2, CAPAN-2, HaCaT, hTCEpi, MCF7, OE19, RT4, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000039068-CDH1
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Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- hSC10.17
- Related Disease
- CD324 associated disorders (e.g., hyperproliferative disorders or neoplastic disorders)
Target
- Alternative Names
- CDH1; cadherin 1, type 1, E-cadherin (epithelial); UVO; CDHE; ECAD; LCAM; Arc-1; CD324; cadherin-1; CAM 120/80; E-Cadherin; uvomorulin; cell-CAM 120/80; epithelial cadherin; cadherin 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial;
- Gene ID
- 999
- UniProt ID
- P12830
REVIEWS AND Q&AS
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Economical
This antibody product is reasonably priced while maintaining excellent quality. We have maintained the integrity of our research while remaining within budget.
dependable service
The customer support is incredibly dependable. When there were problems with our shipments, we got fast replacements as well as timely answers to our questions.
Increased specificity
This product's antibody specificity is very excellent. We can now precisely target specific antigens in our assays thanks to it.
Q&As
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What is an ideal washing condition?
A: Usually PBS or TBS with Tween-20, washing buffers should remove unbound antibodies without removing immobilized antigens or target complexes.
-
Does the provider supply datasheets and a Certificate of Analysis (CoA)?
A: Datasheets and Certificates of Analysis (CoAs) outlining the antibody's parameters, validations, and suggested techniques are supplied by reputable vendors.
-
Can I do an overnight incubation using antibodies?
A: It is true that binding can be improved by an overnight incubation at 4°C, but be sure this doesn't result in non-specific binding or degradation.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone hSC10.17"
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
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| HPAB-0467-WJ-F(E) | Human Anti-CDH1 Recombinant Antibody (clone hSC10.17); Fab Fragment | ELISA, FC | Humanized Fab |
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| CAT | Product Name | Application | Type |
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| HPAB-0467-WJ-S(P) | Human Anti-CDH1 Recombinant Antibody (clone hSC10.17); scFv Fragment | ELISA, FC | Humanized scFv |
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