Anti-Human CDH5 Recombinant Antibody (CAT#: TAB-154CL)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human CDH5. The antibodiess are humanized antibodiess directed that react with human VE-cadherin for use in a human using to inhibit angiogenesis, inhibit tumor metastasis, or treat cell proliferative disorders.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, nuclear membrane & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75875/1842_A1_68_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, nuclear membrane & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75875/1842_A1_68_selected.jpg
Figure 2 IHC staining of human vagina
(Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in superficial layers of squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/ihc_selected.jpg
(Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in superficial layers of squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_B_7_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_B_7_5.jpg
Figure 4 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_5.jpg
Figure 7 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_4_6.jpg
Figure 8 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_9_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_9_8.jpg
Figure 9 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179776-CDH5
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179776-CDH5
Specifications
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- 95% by HPLC
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- CDH5; cadherin 5, type 2 (vascular endothelium); 7B4; CD144; cadherin-5; 7B4 antigen; VE-cadherin; cd144 antigen; endothelial-specific cadherin; vascular endothelial cadherin; cadherin 5, type 2, VE-cadherin (vascular epithelium)
- Gene ID
- 1003
- UniProt ID
- P33151
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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|---|---|---|---|
| MOB-1657z | Mouse Anti-CDH5 Recombinant Antibody (clone 24B9) | WB, FC, ICC, IF, IHC, IP, FuncS | Mouse IgG2a |
| ZG-0169C | Mouse Anti-CDH5 Recombinant Antibody (clone 3G8) | IHC-P, IF | Mouse IgG |
| ZG-0170C | Mouse Anti-CDH5 Recombinant Antibody (clone 8E5) | IHC-P, IF | Mouse IgG |
| VS3-QX209 | Mouse Anti-CDH5 Recombinant Antibody (clone 9F2-6F3-10B1) | IHC | Mouse IgG1 |
| VS3-QX210 | Mouse Anti-CDH5 Recombinant Antibody (clone 8F5-6F3-1A7) | IHC | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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