CytoStream™ Rabbit Anti-CDH5 Recombinant Antibody (VS13-YC194) (CAT#: VS13-YC194)
The CytoStream™ Rabbit Anti-CDH5 Recombinant Antibody is specific for human CDH5. CDH5 participates in adhesion pathways affecting conditions like epithelial sarcoma, interacting with components in calcium and ion binding pathways. The anti-CDH5 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/1000).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, nuclear membrane & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75875/1842_A1_68_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, nuclear membrane & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75875/1842_A1_68_selected.jpg
Figure 2 IHC staining of human vagina
(Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in superficial layers of squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/ihc_selected.jpg
(Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in superficial layers of squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_B_7_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_B_7_5.jpg
Figure 4 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_5.jpg
Figure 7 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_4_6.jpg
Figure 8 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_9_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_9_8.jpg
Figure 9 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179776-CDH5
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179776-CDH5
Specifications
- Immunogen
- Recombinant human VE-cadherin, aa 1-650.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CDH5
- Species Reactivity
- Human
- Applications
- WB, ICC, IF, FC
- Conjugate
- NONE
- Related Disease
- Periapical Granuloma and Epithelioid Sarcoma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 40% Glycerol and 0.1% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/2000
Immunofluorescence (IF-cell): 1/100
Flow cytometry (FC): 1/1000
Target
- Alternative Names
- Cadherin 5; VE-Cadherin; Cadherin 5, Type 2, VE-Cadherin (Vascular Epithelium); Cadherin 5, Type 2 (Vascular Endothelium); Vascular Endothelial Cadherin; 7B4 Antigen; Endothelial-Specific Cadherin;
- Gene ID
- 1003
- UniProt ID
- P33151
- Long Name
- Cadherin 5
- Cellular Localization
- Cell junction Cell membrane
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Mouse Antibody Products
Blocking Antibody Products
Rabbit Monoclonal Antibody Products
Epitope-Specific Antibody Products
IgG Antibody Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-283CQ | Anti-Mouse Cdh5 Recombinant Antibody (E4B9) | FuncS | |
| TAB-283CQ-S(P) | Anti-Mouse Cdh5 Recombinant Antibody scFv Fragment (E4B9) | ELISA, WB, IF | |
| TAB-283CQ-F(E) | Anti-Mouse Cdh5 Recombinant Antibody Fab Fragment (E4B9) | ELISA, WB, IF |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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