Hi-Affi™ Rabbit Anti-CDK6 Recombinant Antibody (clone DS634AB) (CAT#: MOR-0634)
Recombinant Rabbit anti-CDK6 monoclonal antibody for WB, IHC, ICC, FC, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/37_E3_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/37_E3_2_selected.jpg
Figure 2 High expression in placenta
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_A_2_7_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_A_2_7_val_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_B_4_4.jpg
(Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_B_4_4.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_A_8_8.jpg
Figure 5 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_B_8_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_B_8_5.jpg
Figure 6 Colon
(Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes - Gradient Gradient: Descending Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_A_9_3.jpg
(Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes - Gradient Gradient: Descending Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_A_9_3.jpg
Figure 7 Testis
(Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_A_6_6.jpg
(Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2637/10679_A_6_6.jpg
Figure 8 RNA cell line category: Cell line enhanced (MOLT-4, REH)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105810-CDK6
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105810-CDK6
Specifications
- Host Species
- Rabbit
- Derivation
- Phage display library
- Type
- Rabbit IgG
- Specificity
- Human CDK6
- Species Reactivity
- Human
- Clone
- DS634AB
- Applications
- WB, IHC, ICC, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Absolute Mag™ Protein A Agarose
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cyclin-Dependent Kinase 6; Serine/Threonine-Protein Kinase PLSTIRE; Cell Division Protein Kinase 6; EC 2.7.11.22; EC 2.7.11; PLSTIRE; MCPH12; CDKN6
- Gene ID
- 1021
- UniProt ID
- Q00534
Related Resources
p53 Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0343-CN | Rabbit Anti-CDK6 Recombinant Antibody (clone CBACN-141) | WB, IF, IHC, FC | Rabbit IgG |
| MRO-1768-CN | Rabbit Anti-CDK6 Polyclonal Antibody (MRO-1768-CN) | WB, IF, IHC | Rabbit IgG |
| ZG-0614J | Rabbit Anti-CDK6 Recombinant Antibody (clone 8G3) | ELISA, WB, IP | Rabbit IgG |
| VS3-WK832 | Rabbit Anti-CDK6 Recombinant Antibody (VS3-WK832) | WB, ICC, IF, IHC, FC | Rabbit IgG |
| VS3-FY349 | Recombinant Rabbit Anti-CDK6 Antibody (clone R03-2G5) | WB, ICC, IF | Rabbit IgG |
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