Anti-Human CFB Recombinant Antibody Fab Fragment (FB-28.4.2)
CAT#: TAB-059MZ-F(E)
This anti-factor B antibody that blocks the generation of the alternative complement pathway C3 convertase may be used to prevent or modulate the activation or amplification of the activation of the complement system.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/951/170_F11_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line ASC TERT1
Immunofluorescent staining of human cell line ASC TERT1 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1817/1749_A9_28_cr5804bcaa17056_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human prostate
Immunohistochemical staining of human prostate shows strong cytoplasmic and membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1817/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IHC staining of human prostate
Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1832/ihc_selected.jpg
Normal Tissue
Figure 5 Cerebral cortex
Endothelial cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1832/6333_B_8_5.jpg
Normal Tissue
Figure 6 Colon
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1832/6333_A_7_3.jpg
Normal Tissue
Figure 7 Rectum
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1832/6333_A_4_3.jpg
Normal Tissue
Figure 8 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1832/6333_A_8_4.jpg
Normal Tissue
Figure 9 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1832/6333_A_7_5.jpg
Normal Tissue
Figure 10 Lymph node
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1832/6333_A_8_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, EFO-21, fHDF/TERT166, HSkMC, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000243649-CFB
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Specifications
- Immunogen
- Human factor B
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Murine
- Clone
- FB-28.4.2
- Applications
- Enzyme-linked Immunosorbent Assay, Western Blot
- Related Disease
- Diseases associated with the complement system, such as, atypical hemolytic uremic syndrome (aHUS) or paroxysmal nocturnal hemoglobinuria (PNH)
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-059MZ | Anti-Human CFB Recombinant Antibody (FB-28.4.2) | ELISA, WB | |
| TAB-060MZ | Mouse Anti-CFB Recombinant Antibody (TAB-060MZ) | ELISA | Mouse IgG1 |
| TAB-059MZ-S(P) | Anti-Human CFB Recombinant Antibody scFv Fragment (FB-28.4.2) | ELISA, WB | |
| TAB-060MZ-S(P) | Mouse Anti-CFB Recombinant Antibody; scFv Fragment (TAB-060MZ-S(P)) | ELISA | Mouse scFv |
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| TAB-061MZ-S(P) | Human Anti-CFB Recombinant Antibody; scFv Fragment (TAB-061MZ-S(P)) | ELISA | Humanized scFv |
| TAB-061MZ-F(E) | Human Anti-CFB Recombinant Antibody; Fab Fragment (TAB-061MZ-F(E)) | ELISA | Humanized Fab |
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| HPAB-0119-YJ-S(P) | Human Anti-CFB Recombinant Antibody; scFv Fragment (HPAB-0119-YJ-S(P)) | FuncS, Inhib, Block | Humanized scFv |
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| HPAB-AP277-YC | Human Anti-CFB Recombinant Antibody (HPAB-AP277-YC) | ELISA, Inhib | Chimeric (mouse/human) IgG |
| HPAB-AP278-YC | Human Anti-CFB Recombinant Antibody (HPAB-AP278-YC) | ELISA, Inhib | Humanized IgG |
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