Human Anti-CSF2 Recombinant Antibody (PABL-481) (CAT#: PABL-481)
Autoantibody
Recombinant Human Antibody is capable of binding to GM-CSF, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-GM-CSF mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-GM-CSF proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This is a high-affinity anti-(human GM-CSF) autoantibody isolated from a patient suffering from PAP which shows only modest neutralization of GM-CSF bioactivity.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57404/1703_H9_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57404/1703_H9_1_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
Figure 2 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
Specifications
- Immunogen
- Human colony stimulating factor 2 (granulocyte-macrophage)
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human CSF2
- Species Reactivity
- Human
- Applications
- Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Function Assay.
Target
- Alternative Names
- CSF2; colony stimulating factor 2 (granulocyte-macrophage); GMCSF; granulocyte-macrophage colony-stimulating factor; CSF; molgramostin; granulocyte macrophage-colony stimulating factor
- Gene ID
- 1437
- UniProt ID
- P04141
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CSF2"
Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibody Products
Chimeric Antibody Products
Humanized Antibody Products
Human Antibody Products
Neutralizing Antibody Products
Blocking Antibody Products
Rabbit Monoclonal Antibody Products
Fab Antibody Products
IgG Antibody Products
ScFv Antibody Products
ADCC Enhanced Antibody Products
Antibody Magnetic Beads
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-183CT | Mouse Anti-CSF2 Recombinant Antibody (TAB-183CT) | ELISA, FC, WB, Block | Mouse IgG |
| TAB-185CT | Anti-Human GM-CSF (Granulocyte-macrophage colony stimulating growth factor) Recombinant Antibody (4K21) | ELISA, Neut | |
| TAB-183CT-S(P) | Mouse Anti-CSF2 Recombinant Antibody; scFv Fragment (TAB-183CT-S(P)) | ELISA, FC, WB, Block | Mouse scFv |
| TAB-185CT-S(P) | Anti-Human GM-CSF (Granulocyte-macrophage colony stimulating growth factor) Recombinant Antibody scFv Fragment (4K21) | ELISA, Neut | |
| TAB-183CT-F(E) | Mouse Anti-CSF2 Recombinant Antibody; Fab Fragment (TAB-183CT-F(E)) | ELISA, FC, WB, Block | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for PABL-481. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
-2.png)
Application: WB, ELISA, FC, IHC, IP
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
Application: WB, ELISA, Neut, FuncS
Application: Block, IP, IF, FC
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, Inhib, FuncS
Application: Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, Neut, FuncS
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
