Anti-DENV4 E Recombinant Antibody (MRO-1129LC) (CAT#: MRO-1129LC)
This product is a recombinant chimpanzee anti-Dengue virus monoclonal antibody specifically binding to the E protein. This full-length antibody selectively bind and neutralize dengue virus type 1, 2 with lower titer and dengue virus type 3 and 4 with higher titer in the PRNT50 assay. Produced in mammalian cells this antibody product was affinity-purified and could be biotinylated for the immunoassays and treatment studies about Dengue virus infection.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Analysis of Fab binding to DENV-1 or DENV-2.
Fabs 1A5, 1B2, and 1A10 were affinity purified, biotinylated, and used for analysis of binding activity to DENV-1 or DENV-2 by competition ELISA in the presence of competing, unlabeled Fabs.
Chimpanzee Fab Fragments and a Derived Humanized Immunoglobulin G1 Antibody That Efficiently Cross-Neutralize Dengue Type 1 and Type 2 Viruses
Specifications
- Host Species
- Chimpanzee
- Derivation
- Phage display library
- Type
- Chimpanzee antibody
- Specificity
- Dengue virus-4
- Clone
- 1B2
- Applications
- ELISA
- Related Disease
- Dengue virus-4 infection
Applications
- Application Notes
- The DENV4 E antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Dengue virus-4; DENV4; Dengue virus-4 envelope protein E; DENV4 E
- Gene ID
- 5075729
- UniProt ID
- P09866
- Long Name
- Dengue virus-4 envelope protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1118LC | Human Anti-DENV4 E Recombinant Antibody (MRO-1118LC) | ELISA | Human IgG |
MRO-1118LC-S(P) | Human Anti-DENV4 E Recombinant Antibody; scFv Fragment (MRO-1118LC-S(P)) | ELISA | Human scFv |
MRO-1118LC-F(E) | Human Anti-DENV4 E Recombinant Antibody; Fab Fragment (MRO-1118LC-F(E)) | ELISA | Human Fab |
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