Anti-DENV4 E Recombinant Antibody (1A10) (CAT#: MRO-1130LC)
This product is a recombinant chimpanzee anti-Dengue virus-4 monoclonal antibody. 1A10 specifically binds to E protein associated with DENV4 and can be potentially used in the treatment and diagnosis of Dengue virus-4 infection.
Specific Inquiry
IP
Figure 1. Analysis of antigen specificity by radioimmunoprecipitation.
Adioactive 35S-methionine-labeled lysates separately prepared from Vero cells infected with each of the DENV serotypes (D1 to D4) were used for immune precipitation with Fab 1A5 or Fab 1A10.
Goncalvez, A. P., Men, R., Wernly, C., Purcell, R. H., & Lai, C. J. (2004). Chimpanzee Fab fragments and a derived humanized immunoglobulin G1 antibody that efficiently cross-neutralize dengue type 1 and type 2 viruses. Journal of virology, 78(23), 12910-12918.
ELISA
Figure 2 Analysis of Fab binding to DENV-1 or DENV-2.
Fabs 1A5, 1B2, and 1A10 were affinity purified, biotinylated, and used for analysis of binding activity to DENV-1 or DENV-2 by competition ELISA in the presence of competing, unlabeled Fabs.
Chimpanzee Fab Fragments and a Derived Humanized Immunoglobulin G1 Antibody That Efficiently Cross-Neutralize Dengue Type 1 and Type 2 Viruses
Specifications
- Host Species
- Chimpanzee
- Derivation
- Phage display library
- Type
- Chimpanzee antibody
- Specificity
- Dengue virus-4
- Clone
- 1A10
- Applications
- ELISA, WB
- Related Disease
- Dengue virus-4 infection
Applications
- Application Notes
- The DENV4 E antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot.
Target
- Alternative Names
- Dengue virus-4; DENV4; Dengue virus-4 envelope protein E; DENV4 E
- Gene ID
- 5075729
- UniProt ID
- P09866
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Human Antibody Products
Mouse Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1118LC | Human Anti-DENV4 E Recombinant Antibody (MRO-1118LC) | ELISA | Human IgG |
| MRO-1118LC-S(P) | Human Anti-DENV4 E Recombinant Antibody; scFv Fragment (MRO-1118LC-S(P)) | ELISA | Human scFv |
| MRO-1118LC-F(E) | Human Anti-DENV4 E Recombinant Antibody; Fab Fragment (MRO-1118LC-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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