Afuco™ Anti-Human EDAR ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-214CL
Anti-EDAR ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The anti-EDAR monoclonal antibodies can be used in the treatment of X-linked hypohidrotic ectodermal dysplasia and tooth agenesis.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human rectum
Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135960-EDAR
❮
❯
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- X-linked hypohidrotic ectodermal dysplasia; Tooth agenesis
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- EDAR; ectodysplasin A receptor; DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; ECTD10A; ECTD10B; EDA-A1R; tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; downless homolog; ectodysplasin-A receptor; downless, mouse, homolog of; ectodermal dysplasia receptor; anhidrotic ectodysplasin receptor 1; ectodysplasin 1, anhidrotic receptor
- Gene ID
- 10913
- UniProt ID
- Q9UNE0
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for AFC-214CL. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "EDAR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0161CT | Recombinant Mouse anti-Human EDAR Monoclonal antibody (EML1158) | WB | |
| HPAB-0045-LS | Human Anti-EDAR Recombinant Antibody (HPAB-0045-LS) | ELISA, WB, FC | Human IgG1 |
| HPAB-0046-LS | Human Anti-EDAR Recombinant Antibody (HPAB-0046-LS) | ELISA, WB, FC | Human IgG2b |
| FAMAB-1119CQ | Human Anti-EDAR Recombinant Antibody (clone EDAR3) | Agonist, WB, ELISA | Human IgG1 |
| FAMAB-1689CQ | Human Anti-EDAR Recombinant Antibody (clone EDAR12) | Agonist, WB, ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1090 | Hi-Affi™ Rabbit Anti-EDAR Recombinant Antibody (clone DS1090AB) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0065-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0065-YC-S(P)) | ELISA, WB, FC, Agonist | Human scFv |
| HPAB-J0066-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0066-YC-S(P)) | ELISA, WB, FC, Agonist, FuncS | Human scFv |
| HPAB-J0067-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0067-YC-S(P)) | ELISA, Agonist | Human scFv |
| HPAB-J0068-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0068-YC-S(P)) | ELISA, Agonist | Human scFv |
| HPAB-J0069-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0069-YC-S(P)) | ELISA, Agonist | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0065-YC-F(E) | Human Anti-EDAR Recombinant Antibody; Fab Fragment (HPAB-J0065-YC-F(E)) | ELISA, WB, FC, Agonist | Human Fab |
| HPAB-J0066-YC-F(E) | Human Anti-EDAR Recombinant Antibody; Fab Fragment (HPAB-J0066-YC-F(E)) | ELISA, WB, FC, Agonist, FuncS | Human Fab |
| HPAB-J0067-YC-F(E) | Human Anti-EDAR Recombinant Antibody; Fab Fragment (HPAB-J0067-YC-F(E)) | ELISA, Agonist | Human Fab |
| HPAB-J0068-YC-F(E) | Human Anti-EDAR Recombinant Antibody; Fab Fragment (HPAB-J0068-YC-F(E)) | ELISA, Agonist | Human Fab |
| HPAB-J0069-YC-F(E) | Human Anti-EDAR Recombinant Antibody; Fab Fragment (HPAB-J0069-YC-F(E)) | ELISA, Agonist | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY23 | Mouse Anti-EDAR Agonistic Antibody (clone EDAR12) | WB, ELISA, Agonistic assays, SPR | Mouse IgG1, kappa |
| VS-0724-XY24 | Rabbit Anti-EDAR Agonistic Antibody (VS-0724-XY24) | WB, ELISA, Agonistic assays, SPR | Rabbit IgG, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC490 | Recombinant Anti-EDAR Vesicular Antibody, EV Displayed (VS-0425-YC490) | Agonist, ELISA, FC, Cell-uptake |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: WB, ELISA, FC, IHC, IP
Application: WB, ELISA, IF
Application: Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, FC, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
