Anti-Human EDAR Recombinant Antibody
CAT#: TAB-226CL
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human EDAR. The anti-EDAR monoclonal antibodiess can be used in the treatment of X-linked hypohidrotic ectodermal dysplasia and tooth agenesis.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human rectum
Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42292/93789_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135960-EDAR
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Specifications
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- X-linked hypohidrotic ectodermal dysplasia; Tooth agenesis
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- EDAR; ectodysplasin A receptor; DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; ECTD10A; ECTD10B; EDA-A1R; tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; downless homolog; ectodysplasin-A receptor; downless, mouse, homolog of; ectodermal
- Gene ID
- 10913
- UniProt ID
- Q9UNE0
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "EDAR"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1090 | Hi-Affi™ Rabbit Anti-EDAR Recombinant Antibody (clone DS1090AB) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0065-YC | Human Anti-EDAR Recombinant Antibody (HPAB-J0065-YC) | ELISA, WB, FC, Agonist | Human IgG1 |
| HPAB-J0066-YC | Human Anti-EDAR Recombinant Antibody (HPAB-J0066-YC) | ELISA, WB, FC, Agonist, FuncS | Human IgG1 |
| HPAB-J0067-YC | Human Anti-EDAR Recombinant Antibody (HPAB-J0067-YC) | ELISA, Agonist | Human IgG1 |
| HPAB-J0068-YC | Human Anti-EDAR Recombinant Antibody (HPAB-J0068-YC) | ELISA, Agonist | Human IgG1 |
| HPAB-J0069-YC | Human Anti-EDAR Recombinant Antibody (HPAB-J0069-YC) | ELISA, Agonist | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0065-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0065-YC-S(P)) | ELISA, WB, FC, Agonist | Human scFv |
| HPAB-J0066-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0066-YC-S(P)) | ELISA, WB, FC, Agonist, FuncS | Human scFv |
| HPAB-J0067-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0067-YC-S(P)) | ELISA, Agonist | Human scFv |
| FAMAB-0089JF-S(P) | Mouse Anti-EDAR Recombinant Antibody (clone EDAR8); scFv Fragment | WB, FACS, ELISA, FuncS | Mouse scFv |
| FAMAB-0090JF-S(P) | Mouse Anti-EDAR Recombinant Antibody (clone EDAR9); scFv Fragment | WB, FACS, ELISA, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0065-YC-F(E) | Human Anti-EDAR Recombinant Antibody; Fab Fragment (HPAB-J0065-YC-F(E)) | ELISA, WB, FC, Agonist | Human Fab |
| HPAB-J0066-YC-F(E) | Human Anti-EDAR Recombinant Antibody; Fab Fragment (HPAB-J0066-YC-F(E)) | ELISA, WB, FC, Agonist, FuncS | Human Fab |
| HPAB-J0067-YC-F(E) | Human Anti-EDAR Recombinant Antibody; Fab Fragment (HPAB-J0067-YC-F(E)) | ELISA, Agonist | Human Fab |
| FAMAB-0089JF-F(E) | Mouse Anti-EDAR Recombinant Antibody (clone EDAR8); Fab Fragment | WB, FACS, ELISA, FuncS | Mouse Fab |
| FAMAB-0090JF-F(E) | Mouse Anti-EDAR Recombinant Antibody (clone EDAR9); Fab Fragment | WB, FACS, ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY23 | Mouse Anti-EDAR Agonistic Antibody (clone EDAR12) | WB, ELISA, Agonistic assays, SPR | Mouse IgG1, kappa |
| VS-0724-XY24 | Rabbit Anti-EDAR Agonistic Antibody (VS-0724-XY24) | WB, ELISA, Agonistic assays, SPR | Rabbit IgG, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC490 | Recombinant Anti-EDAR Vesicular Antibody, EV Displayed (VS-0425-YC490) | Agonist, ELISA, FC, Cell-uptake |
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