Anti-Human ESR1 Recombinant Antibody
CAT#: TAB-248CL
Recombinant Human monoclonal antibody expressed in CHO binding to Human ESR1. This is an antibody binds to ER-α36, ER-α36 positively regulates HER2 expression and the population of ALDH1 positive breast cancer cells, and suggested that non-genomic estrogen signaling mediated by ER-α36 is involved in maintenance and regulation of breast cancer stem cells.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1134_D1_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1423_D4_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1_G2_1_blue_red_green.jpg
Normal Tissue
Figure 4 Endometrium
Cells in endometrial stroma
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37/288_B_3_3.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (MCF7, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091831-ESR1
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Specifications
- Host Species
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- Store at -20°C. Open under aseptic conditions.
Target
- Alternative Names
- ESR1; estrogen receptor 1
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ESR1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-898-VHH | Recombinant Anti-Human ESR1 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0305MZ | Recombinant Mouse Anti-Human Estrogen Receptor α Antibody (clone 2E6) | IHC | Mouse antibody |
| ZG-0309J | Mouse Anti-ESR1 Recombinant Antibody (ZG-0309J) | WB, ELISA | Mouse IgG |
| ZG-0317J | Mouse Anti-ESR1 Recombinant Antibody (ZG-0317J) | WB, ELISA | Mouse IgG |
| ZG-0318J | Mouse Anti-ESR1 Recombinant Antibody (ZG-0318J) | WB, ELISA | Mouse IgG |
| ZG-0319J | Mouse Anti-ESR1 Recombinant Antibody (ZG-0319J) | WB, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0197MZ | Chicken Anti-ESR1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-750CQ | Mouse Anti-ESR1 Recombinant Antibody (clone 33) | Block, FC, GS, ELISA, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-751CQ | Mouse Anti-ESR1 Recombinant Antibody (clone TE111.5D11) | FC, IP, WB, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1201 | Hi-Affi™ Rabbit Anti-ESR1 Recombinant Antibody (clone DS1201AB) | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY93 | AbPlus™ Anti-ESR1 Magnetic Beads (33) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY193 | Mouse Anti-NHP ESR1 Recombinant Antibody (clone 33) | WB, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2367 | Anti-ESR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2368 | Anti-Mouse ESR1 Immunohistochemistry Kit | IHC |
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