Anti-HIV-1 gp120 Recombinant Antibody (MN215) (CAT#: MRO-157LC)
This product is a recombinant human anti-HIV-1 monoclonal antibody. MN215 specifically binds to gp120 and can be potentially used in the treatment of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.
Specific Inquiry
ELISA
Figure 1. Peptide inhibition ELISA of HuMAb MN215 with V3 loop peptides.
HuMAb MN215 showed a relatively high affinity for the HIV-1 MN peptide and for the HIV-1 Universal V3 and HIV-1 SC peptides, but it bound with a much lower affinity to the HIV-1 SF2 peptide.
Schutten, M., Langedijk, J. P. M., Andeweg, A. C., Huisman, R. C., Meloen, R. H., & Osterhaus, A. D. M. E. (1995). Characterization of a V3 domain-specific neutralizing human monoclonal antibody that preferentially recognizes non-syncytium-inducing human immunodeficiency virus type 1 strains. Journal of general virology, 76(7), 1665-1673.
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- HIV-1
- Clone
- MN215
- Applications
- ELISA
- Related Disease
- AIDS
Applications
- Application Notes
- The MN215 antibody has been reported in applications of ELISA.
It's recommended that the optimal antibody concentration, dilution, incubation time etc. are best to be carefully titrated in specific assays. For details, refer to Published Data.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-082 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-028LC-VHH) | ELISA | Single domain antibody |
| MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-029LC-VHH) | ELISA | Single domain antibody |
| MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-030LC-VHH) | ELISA | Single domain antibody |
| MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-031LC-VHH) | ELISA | Single domain antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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