Anti-HIV-1 gp120 Recombinant Antibody (MN215) (CAT#: MRO-157LC)
This product is a recombinant human anti-HIV-1 monoclonal antibody. MN215 specifically binds to gp120 and can be potentially used in the treatment of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.
Specific Inquiry
ELISA
Figure 1. Peptide inhibition ELISA of HuMAb MN215 with V3 loop peptides.
HuMAb MN215 showed a relatively high affinity for the HIV-1 MN peptide and for the HIV-1 Universal V3 and HIV-1 SC peptides, but it bound with a much lower affinity to the HIV-1 SF2 peptide.
Schutten, M., Langedijk, J. P. M., Andeweg, A. C., Huisman, R. C., Meloen, R. H., & Osterhaus, A. D. M. E. (1995). Characterization of a V3 domain-specific neutralizing human monoclonal antibody that preferentially recognizes non-syncytium-inducing human immunodeficiency virus type 1 strains. Journal of general virology, 76(7), 1665-1673.
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- HIV-1
- Clone
- MN215
- Applications
- ELISA
- Related Disease
- AIDS
Applications
- Application Notes
- The MN215 antibody has been reported in applications of ELISA.
It's recommended that the optimal antibody concentration, dilution, incubation time etc. are best to be carefully titrated in specific assays. For details, refer to Published Data.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone MN215"
See other products for "HIV-1 gp120"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-380 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC06) | FC, Neut, FuncS | Human IgG |
| PABL-520 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 44-VRC13.01) | Neut | Human IgG |
| PABL-521 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-46M2) | ELISA, Neut | Human IgG |
| PABL-522 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-VRC01.H5.F-185917) | WB, FuncS | Human IgG |
| PABL-523 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 8ANC131) | WB, FuncS | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-210 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 19.3H-L1); Fab Fragment | Neut | Human Fab |
| MRO-3532CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 6A); scFv Fragment | ELISA | Humanized scFv |
| MRO-3647CQ-S(P) | Rat Anti-HIV-1 gp120 Recombinant Antibody (clone 11/68b); scFv Fragment | Neut | Rat scFv |
| MRO-3648CQ-S(P) | Rat Anti-HIV-1 gp120 Recombinant Antibody (clone 41.1 (ICR41.1i, ICR41. ICR 41.1i)); scFv Fragment | Neut | Rat scFv |
| MRO-3649CQ-S(P) | Rat Anti-HIV-1 gp120 Recombinant Antibody (clone 62c); scFv Fragment | ELISA | Rat scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-541 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone b13); Fab Fragment | Neut | Human Fab |
| PFBL-543 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone KD-247); Fab Fragment | Neut | Humanized Fab |
| PFBL-546 | Human Anti-HIV-1 gp120 V1V2 domain Recombinant Antibody (clone P4); Fab Fragment | WB, IF, FuncS | Human Fab |
| PFBL-547 | Human Anti-HIV-1 gp120 V1V2 domain Recombinant Antibody (clone PG10); Fab Fragment | WB, IF, FuncS | Human Fab |
| PFBL-548 | Human Anti-HIV-1 gp120 V1V2 region Recombinant Antibody (clone 830A); Fab Fragment | WB, IF, FuncS | Human Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91C2) | ELISA | Single domain antibody |
| MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91F10) | ELISA | Single domain antibody |
| MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91E1) | ELISA | Single domain antibody |
| MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91B5) | ELISA | Single domain antibody |
| MRO-032LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91H9) | ELISA | Single domain antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-125LC | Anti-HIV-1 gp120 Recombinant Antibody (N6) | Neut, ELISA | Human antibody |
| MRO-130LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-130LC) | ELISA, Neut, SPR | Human IgG |
| MRO-136LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900973) | ELISA | Human antibody |
| MRO-137LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900972) | ELISA | Human antibody |
| MRO-138LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900990) | ELISA | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-132LC | Anti-HIV-1 gp120 Recombinant Antibody (BAT123) | ELISA, WB, IF, Neut | Mouse antibody |
| MRO-133LC | Anti-HIV-1 gp120 Recombinant Antibody (BAT267) | ELISA, WB, Neut | Mouse antibody |
| MRO-134LC | Anti-HIV-1 gp120 Recombinant Antibody (BAT085) | ELISA, WB, IF, Neut | Mouse antibody |
| MRO-150LC | Anti-HIV-1 gp120 Recombinant Antibody (G3-4) | ELISA, Inhib, FC, Neut, RIPA, DB, IP | Mouse antibody |
| MRO-152LC | Anti-HIV-1 gp120 Recombinant Antibody (G3-136) | Neut, ELISA | Mouse antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
| MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
| MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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